CORD BLOOD DIAGNOSIS OF COAGULOPATHIES IN HIGH-RISK NEWBORNS

高危新生儿凝血病的脐带血诊断

• 批准号: 3903913
• 负责人: THOMAS ABSHIRE
• 金额: --
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3903913
• 关键词: blood coagulation tests; blood disorder diagnosis; diagnosis design /evaluation; disseminated intravascular coagulation; fibrin; fibrinogen; human pregnant subject; human subject; newborn human (0-6 weeks); plasmin; thrombin

Coagulopathies occur frequently in the sick newborn but are difficult to diagnose because of insensitivities in our current screening tests. This study will measure specific fibrinogen/fibrin fragments to develop a more specific and sensitive test of disseminated intravascular coagulation (DIC) and to discern the role of Thrombin act. or plas. in high risk newborns.

凝血病经常发生在患病的新生儿，但 由于我们目前对疾病的不敏感性， 筛选测试 这项研究将具体衡量 纤维蛋白原/纤维蛋白片段，以开发更特异性和 弥散性血管内凝血（DIC）敏感性试验和 以明确凝血酶的作用。或plas。高危 新生儿