TREATMENT OF 21-HYDROXYLASE DEFICIENCY IN CONGENITAL (CAH) PATIENTS

先天性 (CAH) 患者 21-羟化酶缺乏症的治疗

• 批准号: 3884678
• 负责人: DOROTHY J. BECKER
• 金额: --
• 依托单位: CHILDREN'S HOSP PITTSBURGH/UPMC HLTH SYS
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3884678
• 关键词: adrenal hyperplasia; adrenocorticotropic hormone; congenital disorders; endocrine disorder diagnosis; human subject; human therapy evaluation; pediatrics

Hormonal profiles before and after ACTH stimulation, with patient signs and symptoms, are compared with those in normal individuals to define abnormal responses and make the diagnosis of mild defects possible. Need and effectiveness of treatment is assessed by measuring hormones at specific times after the administration of medication.

促肾上腺皮质激素刺激前后的激素曲线，患者体征和 症状，与正常个体进行比较，以确定异常 反应，使诊断轻度缺陷成为可能。 需要和 治疗的有效性是通过测量特定的激素来评估的。 服用药物后的时间。