HYPOGLYCEMIA IN CHILDHOOD

儿童期低血糖

• 批准号: 3884668
• 负责人: DOROTHY J. BECKER
• 金额: --
• 依托单位: CHILDREN'S HOSP PITTSBURGH/UPMC HLTH SYS
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3884668
• 关键词: arginine; blood glucose; cortisol; free fatty acids; glucagon; homeostasis; hormone regulation /control mechanism; human subject; hypoglycemia; inborn metabolism disorder diagnosis; insulin; ketones; metabolism disorder diagnosis; somatotropin; triglycerides

Determine alterations in normal glucose homeostasis that provokes spontaneous hypoglycemia in childhood. Hormonal and metabolic alterations to glucose, oral glucose ingestion, arginine and insulin infusion, medium chain triglycerides. Assessment of free fatty acids, ketones, growth hormone, cortisol, insulin, glucagon and blood glucose levels after 24-hour fast.

确定正常血糖稳态的变化，从而引发 儿童时期的自发性低血糖。荷尔蒙和代谢变化 对葡萄糖，口服葡萄糖摄取，精氨酸和胰岛素输注，中 链状甘油三酯。游离脂肪酸、酮类、生长发育的评估 24小时后激素、皮质醇、胰岛素、胰高血糖素和血糖水平 快地。