IMMUNOLOGICAL AND VIROLOGICAL STUDIES OF PATIENTS WITH HIV INFECTIONS AND AIDS

HIV 感染和艾滋病患者的免疫学和病毒学研究

• 批准号: 3884428
• 负责人: MILES W CLOYD
• 金额: --
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3884428
• 关键词: AIDS; HIV infections; human immunodeficiency virus 1; human subject; immunologic techniques; pathology; virulence

The progression to clinical disease is due to the Human Immunodeficiency Virus-I is related to a growth characteristic of the infecting strain; i.e., subjects infected with the more rapidly growing HIV isolates are more likely to develop clinical disease earlier due to rapid spread of the virus in vivo. The clinical course of the subjects is related to the presence or absence of HIV-specific immune responses determined in vitro.

发展到临床的疾病是由于人类免疫缺陷 病毒I型与感染株的生长特性有关； 也就是说，感染更快速增长的艾滋病毒分离株的受试者是 由于病毒的快速传播，更有可能更早地发展为临床疾病 体内的病毒。受试者的临床病程与 在体外确定是否存在HIV特异性免疫反应。