INAPPROPRIATE SECRETION OF TSH--A NEW CLINICAL ENTITY

TSH分泌不当——一个新的临床实体

• 批准号: 3884832
• 负责人: CHARLES S HOLLANDER
• 金额: --
• 依托单位: NEW YORK UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3884832
• 关键词: hormone receptor; hormone regulation /control mechanism; human subject; hyperpituitarism; lymphocyte; pituitary neoplasms; radioimmunoassay; thyrotropin; thyrotropin releasing hormone; triiodothyronine

Studies seek to define laboratory parameters that differentiate nonneoplastic causes of pituitary hypersecretion of TSH from pituitary tumors by measuring nuclear receptors for triiodthyronine (T3) on circulating lymphocytes and by radioimmunoassay of TSH and its subunits before and after IV stimulation with thyrotropin-releasing hormone (TRH).

研究试图定义区分 垂体促甲状腺激素分泌过多的非肿瘤原因 三碘甲状腺原氨酸（T3）的核受体， 循环淋巴细胞和TSH及其亚单位的放射免疫测定 在用促甲状腺激素释放激素（TRH）IV刺激之前和之后。