NUCLEAR MAGNETIC RESONANCE SUPERCONDUCTING MAGNET

核磁共振超导磁体

• 批准号: 3520774
• 负责人: JOSEPH A. HELPERN
• 金额: $ 40万
• 依托单位: HENRY FORD HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1990
• 资助国家: 美国
• 起止时间: 1990-06-08 至 1991-06-07
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3520774
• 关键词: biomedical equipment purchase; biomedical equipment resource; image processing; nuclear magnetic resonance spectroscopy

The purpose of this application is to request funds for the upgrade of an existing 1.9 Tesla whole-body Topical Magnetic Resonance (TMR) magnet to a 3.0 Tesla whole-body "flat" magnet for the purpose of applying Nuclear Magnetic Resonance spectroscopy and imaging technology to the study of brain metabolism, cerebral blood flow, and tumor response to therapy. Our present magnet utilizes the technology of TMR as a means of spectroscopic localization. At the time of installation of this magnet, TMR was the only available means for non-invasive spectroscopic localization. Although TMR has been useful in the initial stages of the development of in vivo NMR spectroscopy, it is now considered obsolete technology, and has become inferior to the more efficient volume localization techniques which use switched linear magnetic field gradients (e.g. Image Selective In-Vivo Spectroscopy, ISIS). Our present magnet is now the only magnet of its kind using TMR as the primary means of spectroscopic localization for human in vivo spectroscopy. The present TMR magnet is 100% research dedicated. The upgrade to a 3.0 Tesla "flat" magnet will also be 100% research dedicated, and will provide this concentrated group of NIH supported researchers access to an NMR system which can perform state-of-the-art spectroscopy and imaging.

此申请的目的是请求资金用于升级 现有 1.9 特斯拉全身局部磁共振 (TMR) 磁铁 3.0特斯拉全身“扁平”磁铁，用于核能应用 磁共振波谱和成像技术的研究 脑代谢、脑血流量和肿瘤对治疗的反应。 我们的 目前的磁铁利用TMR技术作为光谱手段 本土化。 在安装该磁铁时，TMR 是唯一的 用于非侵入性光谱定位的可用手段。 虽然TMR 在体内 NMR 发展的初始阶段很有用 光谱学，它现在被认为是过时的技术，并且已经成为 不如使用更有效的体积定位技术 切换线性磁场梯度（例如图像选择性体内 光谱学、ISIS）。我们现在的磁铁是同类中唯一的磁铁 使用TMR作为人体光谱定位的主要手段 活体光谱学。 目前的 TMR 磁体是 100% 研究专用的。 升级至3.0 特斯拉“扁平”磁铁也将 100% 研究专用，并将提供 这个由 NIH 组成的集中小组支持研究人员获得 NMR 可以执行最先进的光谱和成像的系统。