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Quantitative MRI of Iron Homeostasis, Atrophy and Tissue Structure in AD Brain

Quantitative MRI of Iron Homeostasis, Atrophy and Tissue Structure in AD Brain
AD 脑中铁稳态、萎缩和组织结构的定量 MRI
批准号：
8209254
负责人：
JOSEPH A. HELPERN
金额：
$42.82万
依托单位：
MEDICAL UNIVERSITY OF SOUTH CAROLINA
依托单位国家：
美国
项目类别：
财政年份：
2007
资助国家：
美国
项目状态：
已结题
起止时间：
2007-04-15 至 2013-03-31
来源：
https://reporter.nih.gov/project-details/8209254
关键词：
AddressAffectAgeAlzheimer&aposs DiseaseAnisotropyAppearanceAtrophicAxonBiological MarkersBrainBrain regionCell DensityCell membraneClinicalComplexCross-Sectional StudiesDementiaDiagnosisDifferential DiagnosisDiffusionDiffusion Magnetic Resonance ImagingDiseaseDisease ProgressionDoctor of PhilosophyEarly treatmentElderlyEvaluationFutureGoalsHomeostasisImageImpaired cognitionIncidenceIndividualInterventionIronLaboratoriesLongitudinal StudiesMagnetic Resonance ImagingMeasurementMeasuresMedialMonitorNeurodegenerative DisordersOnset of illnessPathogenesisPathologyPatientsPersonsPrevalenceQuantitative EvaluationsResearch PersonnelRiskSpace PerceptionStagingStructureSurrogate MarkersTechniquesTemporal LobeTestingTherapeuticTherapy Clinical TrialsTissuesUnited StatesWorkacronymsbrain tissuecerebral atrophyclinical Diagnosisclinically relevantdensitydrug discoveryfrontal lobeindexinginterestmagnetic fieldmild neurocognitive impairmentnovelpre-clinicalprograms

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期刊论文(13)
专著(0)
科研奖励(0)
会议论文
Progress in diffusion-weighted imaging: concepts, techniques and applications to the central nervous system.
弥散加权成像的进展：概念、技术及其在中枢神经系统中的应用。
DOI： 10.1002/nbm.1589
发表时间： 2010
期刊： NMR in biomedicine
影响因子： 2.9
作者： [Jensen,JensH, Helpern,JosephA]
通讯作者： Helpern,JosephA
Preliminary observations of increased diffusional kurtosis in human brain following recent cerebral infarction.
DOI： 10.1002/nbm.1610
发表时间： 2011-06
期刊： NMR IN BIOMEDICINE
影响因子： 2.9
作者： [Jensen, Jens H., Falangola, Maria F., Hu, Caixia, Tabesh, Ali, Rapalino, Otto, Lo, Calvin, Helpern, Joseph A.]
通讯作者： Helpern, Joseph A.
MRI quantification of non-Gaussian water diffusion by kurtosis analysis.
DOI： 10.1002/nbm.1518
发表时间： 2010-08
期刊： NMR IN BIOMEDICINE
影响因子： 2.9
作者： [Jensen, Jens H., Helpern, Joseph A.]
通讯作者： Helpern, Joseph A.
Preliminary evidence of altered gray and white matter microstructural development in the frontal lobe of adolescents with attention-deficit hyperactivity disorder: a diffusional kurtosis imaging study.
DOI： 10.1002/jmri.22397
发表时间： 2011-01
期刊： JOURNAL OF MAGNETIC RESONANCE IMAGING
影响因子： 4.4
作者： [Helpern, Joseph A., Adisetiyo, Vitria, Falangola, Maria F., Hu, Caixia, Di Martino, Adriana, Williams, Kathleen, Castellanos, Francisco X., Jensen, Jens H.]
通讯作者： Jensen, Jens H.
共 9 条
    Quantitative Neuroimaging Assessment of White Matter Integrity in the Context of Aging and AD
    Quantitative MRI of Microstructure and Iron Homeostasis in ADHD Brain
    Quantitative MRI of Microstructure and Iron Homeostasis in ADHD Brain
    Quantitative MRI of Microstructure and Iron Homeostasis in ADHD Brain
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