ENERGY SPECTRA OF CARDIAC SOUNDS

心音的能量谱

• 批准号: 3899194
• 负责人: R E CLARK
• 金额: --
• 依托单位: NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3899194
• 关键词: heart catheterization; heart surgery; hemodynamics; human subject; mitral valve stenosis; prosthetic heart valve; swine

More than 400 patients have had phonocardiography using a high frequency microphone and accelerometer system. The input is digitized and fast transform fourier analysis applied to the wave fora. Energy in dB versus frequency plots are obtained as are impact or closure sounds to determine synchrony of occluder or leaflet closure. Signatures of normal opening and closing sounds have been obtained. The data were obtained from porcine valves (71 aortic, 124 mitral) and mechanical valves (138 aortic, 58 mitral). More than 100 patients have had the sounds of their prosthetic device measure more than once. Analysis have shown for the aortic porcine that the peak frequency of the systolic ejection murmur is tightly correlated to the frequency of maximal closure energy more than 20 valves have been shown to be dysfunctional both by energy spectra analysis and cardiac catheterization studies. Replacement of the fatigued prosthetic valve has been performed in most cases. Pathologic studies confirm marked leaflet calcification and fatigue. Several more years of tracking the same patient will be required before the predictive value of acoustic energy spectra recording can be established as a screening method for patients with bioprosthetic valves.

超过400名患者使用高血压进行了心音图检查 频率麦克风和加速度计系统。 输入是 数字化快速傅立叶变换分析在波浪中的应用 论坛。 以dB为单位的能量与频率的关系图如下所示： 撞击或闭合声音，以确定封堵器的同步性， 瓣叶闭合。 正常开闭音的特征 已经获得。 数据来自猪瓣膜（71 主动脉瓣124例，二尖瓣124例）和机械瓣膜（主动脉瓣138例，二尖瓣58例）。 100多名患者的假肢发出了声音， 设备测量不止一次。 分析显示主动脉 猪的收缩期喷射杂音的峰值频率是 与最大闭合能的频率密切相关， 超过20个瓣膜已经被证明是功能失调的， 光谱分析和心导管研究。 更换 在大多数情况下，已经进行了疲劳人工瓣膜的修复。 病理学研究证实了明显的瓣叶钙化， 疲劳 对同一个病人再追踪几年 在声能谱的预测值之前， 记录可作为患者的筛选方法 生物瓣膜