MEPERIDINE AND LOCAL ANESTHETICS IN BREAST MILK

母乳中的哌替啶和局部麻醉剂

• 批准号: 3905454
• 负责人: BETTY R. KUHNERT
• 金额: --
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3905454
• 关键词: blood chemistry; colostrums; drug adverse effect; drug metabolism; embryo /fetus drug adverse effect; embryo /fetus pharmacology; human fetus tissue; human milk; human subject; local anesthetics; meperidine; neurologic manifestations; newborn human (0-6 weeks); pharmacokinetics; urinalysis

The purpose of this study is to quantitate the levels of meperidine and bupivacaine in colostrum and breast milk in neonatal plasma and urine and to determine their effects on neonatal behavior. The study includes fetal exposure to meperidine and bupivacaine intrapartum, and neonatal exposure to meperidine administered to the mother for post partum relief.

这项研究的目的是定量测定度冷丁的水平。 和布比卡因在初乳和母乳中的新生儿血浆和 并确定它们对新生儿行为的影响。这个 研究包括胎儿接触度冷丁和布比卡因 产中和新生儿暴露于度冷丁 母亲要求产后救济。