CONTROL OF ADRENAL SECRETION

控制肾上腺分泌

• 批准号: 3907462
• 负责人: GORDON N WILLIAMS
• 金额: --
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3907462
• 关键词: Cushing's syndrome; adrenal hypertension; aldosterone; angiotensin /renin /aldosterone hypertension; angiotensin II; hormone regulation /control mechanism; human subject; potassium; secretion; vasoconstriction

The area under investigation is the regulation of aldosterone secretion by angiotensin II as well as potassium ions in patients with primary aldosteronism in contrast to those with cushing's syndrome. Other forms of secondary hypertension (renal artery stenosis, pheochromocytoma, and accelerated essential hypertension) are being evaluated on similar protocols, as controls for those patients who have adrenal cortical causes of hypertension.

正在研究的领域是调节醛固酮分泌 血管紧张素II以及钾离子在原发性 醛固酮增多症与库欣综合征形成对比。其他形式 继发性高血压（肾动脉狭窄，嗜铬细胞瘤， 加速原发性高血压）正在评估类似的 方案，作为那些患有肾上腺皮质疾病的患者的对照 高血压的原因