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NATURAL HISTORY OF ARTHRITIS AND RHEUMATISM ON THE GILA RIVER INDIAN COMMUNITY

NATURAL HISTORY OF ARTHRITIS AND RHEUMATISM ON THE GILA RIVER INDIAN COMMUNITY
吉拉河印第安社区关节炎和风湿病的自然史
批准号：
3918287
负责人：
P H BENNETT
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3918287
关键词：
Native Americans arthritis disease /disorder proneness /risk environmental health epidemiology gender difference genetic markers human age group human population genetics human subject interview joint disorder juvenile rheumatoid arthritis leukocyte antigen typing longitudinal human study musculoskeletal disorder diagnosis orphan disease /drug osteoarthritis prognosis radiography rheumatoid arthritis rheumatoid factor serology /serodiagnosis

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中文摘要
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英文摘要
The development and progression of osteoarthrosis, rheumatoid arthritis and ankylosing spondylitis are being determined by means of clinical, radiographic and serological examinations carried out prospectively at two-yearly intervals among adults of the Gila River Indian Community (Pima Indians) in Arizona, in conjunction with epidemiological studies of diabetes in the same community. The purpose of this investigation is to ascertain the determinants of these diseases in the population, and to identify factors which alter the natural history of progression of the disease. Host factors such as age, sex, and various gene markers including HLA and Gm, together with various potential environmental determinants, such as obesity and evidence of exposure to infectious agents, will be studied prospectively to determine their relationship to the development of these diseases. Longitudinal data have now been collected over 20 years and represent a unique data set for epidemiological studies of arthritis.
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GILA RIVER INDIAN COMMUNITY AUTOPSY AND MORTALITY STUDY
GILA RIVER INDIAN COMMUNITY AUTOPSY AND MORTALITY STUDY
DIABETES, ARTHRITIS, AND OTHER METABOLIC DISEASES IN THE PACIFIC REGION
NATURAL HISTORY OF ARTHRITIS AND RHEUMATISM ON THE GILA RIVER INDIAN COMMUNITY
国内基金
海外基金
Autoimmune diseases therapies: variations on the microbiome in rheumatoid arthritis
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data