CONGENITAL THROMBOTIC DISEASE IN PEDIATRICS

儿科先天性血栓性疾病

• 批准号: 3925191
• 负责人: MARILYN J MANCO-JOHNSON
• 金额: --
• 依托单位: UNIVERSITY OF COLORADO DENVER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3925191
• 关键词: antithrombin III; blood coagulation; blood coagulation tests; blood proteins; cardiovascular disorder diagnosis; child (0-11); congenital blood disorder; congenital cardiovascular disorder; human subject; pathologic process; pediatrics; protein C; thrombosis

Children with congenital thrombotic disorder including deficiencies of AT-III, protein C and protein S will be evaluated with detailed functional and structural analysis of the deficient or defective protein. Where clinically indicated, therapeutic trials will be conducted.

包括缺陷在内的先天性血栓形成障碍的儿童 AT-III、蛋白C和S蛋白将进行详细的评估 缺陷或缺陷词的功能和结构分析 蛋白。在临床显示的情况下，治疗试验将 指挥。