X-RAY DIFFRACTIOMETER--RIGAKU, D/MAX-RVBX & PSPC/MDG

X射线衍射仪--RIGAKU, D/MAX-RVBX

• 批准号: 3519850
• 负责人: TAKAAKI AOBA
• 金额: $ 13.9万
• 依托单位: ADA FORSYTH INSTITUTE, INC.
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-05-16 至 1989-05-15
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3519850
• 关键词: X ray crystallography; biomedical equipment purchase; biomedical equipment resource

This proposal is for the acquisition of a Rigaku X-ray diffractometer system, the D/max-B series and X-ray micro diffraction unit, to replace a 25 year-old X-ray diffractometer. X-ray diffractometry is an important technique which is used or required by investigators from most of the departments at this Institution (Physical Chemistry, Inorganic Chemistry, Biochemistry, Bioengineering, Cariology, Dental materials, Ultrastructure and Histology). Investigators in these departments are engaged in research in the following areas: dental cariogenesis, preparation and solubility studies of hydroxy- and fluorapatites as prototypes of biological apatites, mineralization and structure of tooth and bone, and dental materials. Effective work on problems in these areas requires a superior diffractometer, capable of efficient, qualitative and quantitative, and microanalytical approaches. The proposed instrument will meet these needs: a) high intensity supply using a rotating anode, b) alignment and data analysis by a computer, and c) microbeam diffraction techniques with the position sensitive proportional counter (PSPC). The high power supply will shorten the measuring times, improve the accuracy of measurements with a support from the computer, and provide sufficient intensity even if the generated x-ray beam is collimated for the microbeam diffraction (10, 30 and 100 um in diameters). A highly significant further issue is that the proposed instrument has major advantages with respect to safety in that operator exposure to X-radiation is negligible and the instrument has interlocks which prevent accidental exposure of operators to X-radiation. These feature are absent from the existing equipment. A significant number of the anticipated research projects involve correlating morphological and histological features with the crystallographic properties of mineralized tissues and dental materials. The proposed microbeam diffractometer will fulfil these needs by providing PSPC to simultaneously accumulate diffraction intensity data for a wide-range of 20 angles from 5 through 150: In addition, the diffraction data can be obtained, using the proposed instrument, from a large number of small areas in the specimen within reasonable working times, thus providing an invaluable tool to ascertain the degree of heterogeneity of specimens. For the foregoing reasons we strongly believe that the new equipment would constitute a very significant enhancement of our Institute's capabilities in the area of dental research.

这项提议是为了收购一台Rigaku X光机 衍射仪系统、D/max-B系列和X射线显微镜 更换已有25年历史的X射线衍射仪。 X射线衍射仪是一项重要的技术，它被用来或 来自大多数部门的调查人员要求 研究所(物理化学、无机化学、 生物化学、生物工程、龋齿、牙科材料、 超微结构和组织学)。这些部门的调查人员 从事以下领域的研究：牙科 羟基-2，4-羟基丁二烯的致龋性、制备及溶解度研究 氟磷灰石作为生物磷灰石的原型，矿化 牙齿和骨骼的结构，以及牙科材料。有效 解决这些领域的问题需要一位上级 衍射仪，能够高效，定性和定量， 和微量分析方法。 拟议的文书将满足这些需要：a)高强度 使用旋转阳极供电，b)由a)对准和数据分析 计算机，以及c)微束衍射技术 位置灵敏比例计数器(PSPC)。强大的力量 供货将缩短测量时间，提高测量精度 在计算机的支持下测量，并提供 即使产生的x射线束具有足够的强度 准直用于微束衍射(10、30和100微米英寸 直径)。另一个非常重要的问题是，拟议的 仪器在安全性方面有很大的优势 操作员受到的X射线照射可以忽略不计，仪器 有联锁装置，可防止操作员意外接触 X-射线。这些功能在现有的 设备。 大量预期的研究项目涉及 形态和组织学特征与 矿化组织和牙科的结晶学特性 材料。所提出的微束衍射仪将满足 这些需求通过提供PSPC来同时积累 从5到20个角度的大范围的衍射强度数据 至150：此外，还可以获得衍射数据， 使用建议的仪器，从大量的小区域 在合理的工作时间内保存在样品中，从而提供 这是一种非常有价值的工具，用于确定 标本。基于上述原因，我们坚信 新设备将是一项非常重大的改进 我们研究所在牙科研究领域的能力。