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GENETICS OF REPRODUCTIVE LONGEVITY IN DROSOPHILA

果蝇生殖寿命的遗传学

基本信息

批准号：
3114288
负责人：
YUICHIRO HIRAIZUMI
金额：
$ 8.45万
依托单位：
UNIVERSITY OF TEXAS AT AUSTIN
依托单位国家：
美国
项目类别：
财政年份：
1979
资助国家：
美国
起止时间：
1979-09-29 至 1989-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/3114288
关键词：
aging animal population genetics chromosomes cytogenetics environmental adaptation fertility gender difference genes genetic regulation genotype life cycle mature animal natural selections spermatogenesis temperature sensitive mutant

项目摘要

Fitness is a complex parameter which is determined by many factors in the life-history of a genotype. One way to measure the fitness of a genotype will be to make use of Fisher's Malthusian parameter m, which is defined as a real root of the equation, where 1(x) is the survival rate of a genotype to age x, f(x) is the fecundity at age x, t is the age when the genotype starts to produce progeny and T is the age when the genotype terminates reproduction. In Drosophila, T contributes only little in determining m so that 1(x), f(x) and t may be considered as 3 major factors in the life-history. Using Drosophila melanogaster as an experimental material, the present study attempts to examine the relationships among these components of fitness for various inbred lines of various origins as well as for wild strains from natural populations. It is also attempted to example the effects of environmental conditions (temperature) upon each component of fitness. Investigations will be conducted at different temperature conditions for not only those strains mentioned above but also the artificially synthesized milk-bottle populations.

适应度是一个复杂的参数，它是由许多因素决定的，基因型的生活史衡量基因型适合度的一种方法将使用Fisher的马尔萨斯参数m，其定义为：方程的真实的根，其中1（x）是基因型的存活率 f（x）是x岁时的繁殖力，t是基因型在x岁时的年龄，开始产生后代，T是基因型终止的年龄生殖在果蝇中，T在决定m so方面贡献很小。 1（x），f（x）和t可以被认为是3个主要因素，生活史以黑腹果蝇为实验材料，这项研究试图研究这些组成部分之间的关系，适合于各种来源的各种近交系以及野生的来自自然种群的菌株。还试图举例说明环境条件（温度）对健身研究将在不同温度下进行不仅上述那些菌株的条件，人工合成的奶瓶种群。

项目成果

期刊论文数量（12）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Predictors of diminished levels of social integration in older adults.

老年人社会融合水平下降的预测因素。

DOI：
10.3928/19404921-20130918-02
发表时间：
2014
期刊：
Research in gerontological nursing
影响因子：
1.6
作者：
NicholsonJr,NicholasR;Dixon,JaneK;McCorkle,Ruth
通讯作者：
McCorkle,Ruth

Impact of dopant-induced band tails on optical spectra, charge carrier transport, and dynamics in single-crystal CdTe.

DOI：
10.1038/s41598-022-16994-7
发表时间：
2022-07-27
期刊：
SCIENTIFIC REPORTS
影响因子：
4.6
作者：
Scajev, Patrik;Mekys, Algirdas;Subacius, Liudvikas;Stanionyte, Sandra;Kuciauskas, Darius;Lynn, Kelvin G.;Swain, Santosh K.
通讯作者：
Swain, Santosh K.

Genetics of factors affecting the life history of Drosophila melanogaster. I. Female productivity.

影响果蝇生活史的因素的遗传学。