The Centre for Neuropsychiatric Genetics and Genomics

神经精神遗传学和基因组学中心

• 批准号: G0801418/1
• 负责人: Michael Owen
• 金额: $ 317.68万
• 依托单位: CARDIFF UNIVERSITY
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2009
• 资助国家: 英国
• 起止时间: 2009 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=G0801418%2F1
• 关键词: Centre; Neuropsychiatric; Genetics; Genomics

The goal of the Centre is to understand the genetics of a range of common causes of psychiatric disorders and dementia and to use this understanding to improve the diagnosis and treatment of these disorders. Genes play an important role in disorders such as schizophrenia, bipolar disorder, depression, attention deficit disorder, Alzheimer disease and Parkinson disease. The genetics of these common disorders is complex and it is likely that many genes are involved. However, using modern genetic methods it is now possible to begin to identify the specific genetic abnormalities that underlie common diseases. The core of the Centre?s mission over the next 5 years will be to continue work aimed at identifying genes underlying all of the above disorders. However, there will be an increasing emphasis upon using the knowledge gained to benefit patients via improved understanding of disease mechanisms, better diagnosis and ultimately the development of new treatments.

该中心的目标是了解精神疾病和痴呆症的一系列常见原因的遗传学，并利用这种理解来改善这些疾病的诊断和治疗。基因在精神分裂症、双相情感障碍、抑郁症、注意力缺陷障碍、阿尔茨海默病和帕金森病等疾病中起着重要作用。这些常见疾病的遗传学是复杂的，很可能涉及许多基因。然而，利用现代遗传学方法，现在有可能开始确定常见疾病背后的特定遗传异常。中心的核心？在未来5年中的使命将是继续致力于鉴定上述所有疾病的潜在基因。然而，人们将越来越重视利用所获得的知识，通过提高对疾病机制的理解，更好的诊断和最终开发新的治疗方法来使患者受益。