Understanding pregnant women's uptake of malaria prevention interventions: The role of qualitative evidence

了解孕妇接受疟疾预防干预措施的情况：定性证据的作用

• 批准号: G0802009/1
• 负责人: Helen Smith
• 金额: $ 22.89万
• 依托单位: Liverpool School of Tropical Medicine
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2009
• 资助国家: 英国
• 起止时间: 2009 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=G0802009%2F1
• 关键词: Understanding; pregnant; women; uptake; malaria

Malaria infection in pregnancy is an important public health concern in many developing countries because of the serious consequences for mothers and infants. Pregnant women living in countries where malaria is prevalent are more susceptible to malaria infection than non-pregnant women, and prompt treatment and access to effective measures to prevent malaria depends on women having access to good quality antenatal care services. International donors and regional leaders have recently renewed their commitment to reaching more pregnant women with effective malaria prevention interventions. It is known that pregnant women who regulalry use insecticide-treated nets (ITNs) throughout pregnancy and receive at least two doses of antimalarial drugs during the second and third trimesters (Intermittent Preventive Treatment or IPT) are less likely to acquire malaria or suffer the serious consequences of infection, which can be fatal.Malaria control programmes have struggled to implement simple and effective interventions like IPT or ITNs, in part because they have failed to take account of community and pregnant women?s reactions and responses to the interventions. International donors heavily promote these important public health interventions to try and increase coverage in communities affected by malaria, but the real challenge lies in improving implementation to encourage uptake of ITNs and IPT by pregnant women.This research will bring together all the available evidence on barriers and facilitators to pregnant women?s access and use of ITNs and IPT, women?s acceptability of the interventions, and factors influencing their uptake. Researchers based at Liverpool School of Tropical Medicine together with colleagues working in malaria control in Africa will do this by using a method called research synthesis that summarises results from across multiple studies. Synthesis makes research findings more accessible by bringing a body of evidence to policy makers in a more succinct format. The benefits to malaria control programmes in Africa of a critical and systematic summary of this research are obvious; equipped with evidence of what is important to pregnant women and communities, the design and implementation of programmes to improve the use of IPT and ITNs in pregnancy could be made more effective.Increasing the number of women using ITNs and taking preventive doses of antimalarial treatment during pregnancy is critical to maternal and child health and survival, and in achieving millennium development goals 4, 5 and 6.

妊娠期疟疾感染对母亲和婴儿造成严重后果，是许多发展中国家的一个重要公共卫生问题。生活在疟疾流行国家的孕妇比非孕妇更容易感染疟疾，及时治疗和获得有效预防疟疾的措施取决于妇女能否获得优质产前保健服务。国际捐助者和地区领导人最近再次承诺为更多孕妇提供有效的疟疾预防干预措施。众所周知，在整个怀孕期间定期使用经杀虫剂处理的蚊帐 (ITN) 并在妊娠中期和晚期接受至少两剂抗疟药物（间歇性预防治疗或 IPT）的孕妇，感染疟疾或遭受可能致命的严重感染后果的可能性较小。疟疾控制计划一直在努力实施简单而有效的干预措施，如 IPT 或 ITN，部分原因是 因为他们没有考虑到社区和孕妇对干预措施的反应和反应。国际捐助者大力推动这些重要的公共卫生干预措施，试图扩大受疟疾影响的社区的覆盖范围，但真正的挑战在于改善实施情况，以鼓励孕妇接受驱虫蚊帐和IPT。这项研究将汇集所有现有证据，了解孕妇获得和使用驱虫蚊帐和IPT的障碍和促进因素、妇女对干预措施的接受程度以及影响其采用的因素。利物浦热带医学院的研究人员与非洲疟疾控制工作的同事将通过一种称为研究综合的方法来实现这一目标，该方法总结了多项研究的结果。综合以更简洁的形式向政策制定者提供大量证据，使研究结果更容易获得。对这项研究进行批判性和系统性的总结对非洲的疟疾控制计划的好处是显而易见的；有了对孕妇和社区重要的证据，就可以更有效地设计和实施改善孕期异烟肼和驱虫蚊帐的使用的计划。增加怀孕期间使用驱虫蚊帐和预防性抗疟治疗的妇女人数对于孕产妇和儿童的健康和生存以及实现千年发展目标 4、5 和 6 至关重要。