QUANTITATIVE ANALYSIS OF T1-201 CARDIAC SPECT IMAGES

T1-201 心脏频谱图像的定量分析

• 批准号: 3963116
• 负责人: A VAN LINGE
• 金额: --
• 依托单位: CLINICAL CENTER
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3963116
• 关键词: clinical biomedical equipment; heart disorder diagnosis; heart imaging /visualization /scanning; human subject; image processing; nuclear medicine; physics; radionuclide diagnosis; radionuclide imaging /scanning

As part of an effort to study the ability of T1-201 SPECT imaging to assess hypoertrophic cardiomyopathies, several methods of quantiating the clinical images are being assessed. Primarily these are of the circumferential profile type. In addition, a quantitative method for performing scatter correction is being evaluated by observing whether an increase in sensitivity/specificity is obtained upon applying the scatter correction. Thus, rather than simply observing whether the scatter correction algorithm is able to improve the appearance of phantoms, the more clinically relevant question of whether there is a practical improvement in diagnostic ability is addressed. To data, data from 50 normal volunteers has been gathered, and a database of quantitative values extracted from these studies has been organized. In addition, preliminary data necessary for application of the scatter correction algorithm has been acquired, and the effects of noise and filtering is being assessed.

作为研究T1-201SPECT显像评估能力的一部分 低营养性心肌病的几种临床量化方法 正在对图像进行评估。主要是圆周的 配置文件类型。此外，还提供了一种进行散射的定量方法， 修正的评估是通过观察是否增加 在应用散射校正时获得灵敏度/特异度。 因此，不是简单地观察散射校正算法是否 能够改善幻影的外观，更具有临床意义 关于诊断能力是否有实际提高的问题 都被解决了。 收集了50名正常志愿者的数据，并建立了数据库 对从这些研究中提取的量化价值进行了组织。在……里面 此外，应用散布所需的初步数据 获得了校正算法，并对噪声和噪声的影响进行了分析 正在对过滤进行评估。