OPERATION FOR HYPERTROPHIC SUBAORTIC STENOSIS IN THE ELDERLY

老年人肥厚性主动脉下狭窄的手术治疗

• 批准号: 3966648
• 负责人: M M COOPER
• 金额: --
• 依托单位: NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3966648
• 关键词: aging; aortic valve stenosis; heart output disorder; human subject; human therapy evaluation; hypertrophic myocardiopathy; longitudinal human study; medical complication

A retrospective review of 52 patients 65 years and older with hypertrophic cardiomyopathy who had a left ventricular septal myectomy performed. The mean follow up interval was 54 months. No patient has required reoperation. A reduction in left ventricular outflow tract obstruction of 85% was achieved. Symptomatic and functional improvement rates were 85 and 78% respectively an average of 1.3 classes (NYHA). The actuarial survival was 82% at five years. It was concluded that age greater than 65 years is not a contraindication to the operation which significantly improved both quality and duration of life.

52例65岁及以上老年肥厚患者的回顾分析 心肌病患者接受了左室间隔肌切除术术。这个 平均随访时间54个月。没有患者需要 重新手术。左室流出道梗阻的减少 达到了85%。症状和功能改善率分别为85%和 78%分别为平均1.3级(NYHA)。精算生存 5年时为82%。得出的结论是，65岁以上的人 不是手术的禁忌症，手术显著改善了 生活质量和持续时间。