Development of interventions to enhance health and wellbeing in later life (The LIVEWELL programme)

制定干预措施以增强晚年的健康和福祉(LIVEWELL 计划)

基本信息

  • 批准号:
    G0900686/1
  • 负责人:
  • 金额:
    $ 286.27万
  • 依托单位:
  • 依托单位国家:
    英国
  • 项目类别:
    Research Grant
  • 财政年份:
    2010
  • 资助国家:
    英国
  • 起止时间:
    2010 至 无数据
  • 项目状态:
    已结题

项目摘要

Although we are living longer than in previous generations, in many cases the greater number of life years includes more years of chronic poor health so that much of humankind?s experience of ill-health and expenditure on medical and social care (especially in Western countries) are concentrated in the later years of life. The challenge is to finds ways of improving health and maintaining wellbeing throughout the life-course. There is very good evidence that behavioural factors (smoking, diet, alcohol consumption, physical activity) and social conditions are strongly associated with health and wellbeing in later life. However, there is very little evidence about practical interventions to change these factors that are effective in promoting improved health and wellbeing in later life. The LIVEWELL programme is designed to address this research gap by identifying i) types of intervention that are expected to be feasible, effective, and cost effective i.e. behavioural and social changes that can be incorporated into everyday life and ii) windows of opportunity when interventions are likely to be most effective. In addition we will develop tools for measuring change in health and wellbeing in response to interventions ? lack of such tools is a significant limitation on current research attempting to improving health and wellbeing in later life. We plan to focus on the ?retirement window? i.e. the period before and after when the main income provider in a household retires from primary employment. In discussion with older people about what they think would be feasible and attractive and on the basis of the best research evidence available, we will develop interventions will address each of the main behavioural and social factors which are likely to be modifiable. This will include novel interventions in the areas of diet (encouraging a Mediterranean eating pattern), physical activity (e.g. walking and swimming) and social interactions. We will integrate these new interventions with more established interventions on smoking cessation and moderation in alcohol consumption to develop a package of interventions which, when appropriate, can be tailored to the needs of individuals and communities. Further, we will develop novel ways of delivering these interventions which will be feasible and cost-effective and which will encourage sustained behaviour change and improved social circumstances in preparation for later studies to test the intervention package.
虽然我们比前几代人活得更长,但在许多情况下,更多的生命年数包括更多的慢性健康状况不佳的年份,因此,人类的许多人?老年人的健康状况不佳的经历以及医疗和社会保健支出(特别是在西方国家)集中在晚年。我们面临的挑战是找到在整个生命过程中改善健康和保持幸福的方法。有很好的证据表明,行为因素(吸烟,饮食,饮酒,体育活动)和社会条件与晚年的健康和福祉密切相关。然而,很少有证据表明实际干预措施可以改变这些因素,从而有效地促进晚年的健康和福祉。LIVEWELL计划旨在通过确定i)预期可行,有效和具有成本效益的干预类型,即可以纳入日常生活的行为和社会变化,以及ii)干预可能最有效的机会窗口来解决这一研究空白。此外,我们将开发工具,用于衡量健康和福祉的变化,以应对干预措施?缺乏这些工具是目前试图改善晚年健康和福祉的研究的一个重大限制。我们计划把重点放在?退休窗口?即家庭主要收入提供者从主要职业退休前后的时期。在与老年人讨论他们认为什么是可行的和有吸引力的,并在现有的最佳研究证据的基础上,我们将制定干预措施,以解决每一个可能改变的主要行为和社会因素。这将包括在饮食(鼓励地中海饮食模式)、体育活动(如散步和游泳)和社会交往等领域采取新的干预措施。我们将把这些新的干预措施与更成熟的戒烟和节制饮酒干预措施相结合,以制定一套干预措施,酌情根据个人和社区的需要进行调整。此外,我们将开发新的方法来提供这些干预措施,这些方法将是可行的和具有成本效益的,并将鼓励持续的行为改变和改善社会环境,为以后的研究做好准备,以测试干预方案。

项目成果

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John Mathers其他文献

OR25-07-23 Abbreviated Score To Assess Adherence to the 2018 WCRF/AICR Cancer Prevention Recommendations and Risk of Cancer in the UK Biobank Cohort
  • DOI:
    10.1016/j.cdnut.2023.100457
  • 发表时间:
    2023-07-01
  • 期刊:
  • 影响因子:
  • 作者:
    Fiona Malcomson;Solange Parra-Soto;Frederick Ho;Carlos Celis-Morales;Linda Sharp;John Mathers
  • 通讯作者:
    John Mathers
OR06-04-23 Objectively Measured Physical Activity and Risk of Colorectal Cancer: Evidence From the UK Biobank Cohort Study
  • DOI:
    10.1016/j.cdnut.2023.101761
  • 发表时间:
    2023-07-01
  • 期刊:
  • 影响因子:
  • 作者:
    Solange Parra-Soto;Fiona Malcomson;John Mathers;Frederick Ho;Katrina Knight;Jill Pell;Carlos Celis-Morales
  • 通讯作者:
    Carlos Celis-Morales
SAT146 - A meditarranean diet intervention has beneficial effects on biomarkers of cardiovascular risk and hepatic fibrosis in non-alcoholic fatty liver disease (NAFLD)
SAT146 - 地中海饮食干预对非酒精性脂肪肝疾病(NAFLD)中心血管风险和肝纤维化的生物标志物具有有益影响
  • DOI:
    10.1016/s0168-8278(22)01788-3
  • 发表时间:
    2022-07-01
  • 期刊:
  • 影响因子:
    33.000
  • 作者:
    Laura Haigh;Olivier Govaere;Lorna Brownlee;Sarah Charman;Alasdair Blain;Thomas Wilson;Morten Karsdal;Stuart Mcpherson;John Mathers;Quentin Anstee
  • 通讯作者:
    Quentin Anstee
P32. Buccal cells as a surrogate DNA source for methylation biomarkers to identify those at increased colorectal cancer risk
  • DOI:
    10.1016/j.ejso.2012.07.153
  • 发表时间:
    2012-11-01
  • 期刊:
  • 影响因子:
  • 作者:
    Helen Staley;David Bradburn;John Mathers
  • 通讯作者:
    John Mathers
P23-010-23 Plasma miR-15a Levels Are Associated With Dietary Inflammatory Index and Inflammatory Status in Women: The 2015 ISA-Nutrition Study
  • DOI:
    10.1016/j.cdnut.2023.100123
  • 发表时间:
    2023-07-01
  • 期刊:
  • 影响因子:
  • 作者:
    Paula Brandão-Lima;Fiona Malcomson;Tanyara Payolla;Gabrielli Carvalho;Flávia Sarti;Regina Mara Fisberg;Michael Wirth;James Hébert;John Mathers;Marcelo Rogero
  • 通讯作者:
    Marcelo Rogero

John Mathers的其他文献

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{{ truncateString('John Mathers', 18)}}的其他基金

BBSRC DRINC Training Grant 2010
BBSRC DRINC 培训补助金 2010
  • 批准号:
    BB/H532067/1
  • 财政年份:
    2010
  • 资助金额:
    $ 286.27万
  • 项目类别:
    Training Grant
Impact of non-digestible carbohydrates on biomarkers of GI health: a human intervention study
不可消化的碳水化合物对胃肠道健康生物标志物的影响:一项人类干预研究
  • 批准号:
    BB/H005013/1
  • 财政年份:
    2010
  • 资助金额:
    $ 286.27万
  • 项目类别:
    Research Grant
DNA Methylation Developmental Programming and Cellular Memory: The Molecular Consequences of Folate Depletion In Utero
DNA 甲基化发育编程和细胞记忆:子宫内叶酸消耗的分子后果
  • 批准号:
    BB/G007993/1
  • 财政年份:
    2009
  • 资助金额:
    $ 286.27万
  • 项目类别:
    Research Grant

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儿童期受虐经历影响成年人群幸福感:行为、神经机制与干预研究
  • 批准号:
    32371121
  • 批准年份:
    2023
  • 资助金额:
    50.00 万元
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A Brief Intervention to Enhance Supportive Parenting and Treatment Engagement Among Families Waiting for Trauma-Focused Services
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  • 批准号:
    10644434
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