CLINICAL PHENOMENA IN SCHIZOPHRENIA--QUANTIFICATION IN A EFFORT TO SUBTYPE
CLINICAL PHENOMENA IN SCHIZOPHRENIA--QUANTIFICATION IN A EFFORT TO SUBTYPE
批准号:
3968571
负责人:
C N KARSON
金额:
$0.0万
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
关键词:
aggression anxiety cerebrospinal fluid clinical chemistry cognition disorders depression disease /disorder classification eye disorder diagnosis fear human subject kidney function mental disorder chemotherapy mental disorder diagnosis paranoid schizophrenia schizophrenia tardive dyskinesia vasopressins
中文摘要
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英文摘要
Despite wide variations in the clinical manifestations of schizophrenia, it
remains difficult for clinicians to design novel treatments or predict
vulnerability to negative outcomes (including medication side effects)
based on signs and symptoms of the disorder. By focusing on certain
clinical characteristics of schizophrenia we have designed a series of
experimental medication treatments. This involves the notion that the
disorder is associated with impaired cognitive performance. Hence, we have
begun trials of medication that may improve cognition. Our first such
trial utilized DDAVP with at least modest success.
In addition we have looked for clinical manifestations potentially
associated with poor outcomes. We have found that patients with
schizophrenia are more assaultive than other seriously ill psychiatric
patients while in the hospital and that a previous history of assaultive is
associated with an increased number of hospitalizations. With regards to
the major side effect of neuroleptic treatment, tardive dyskinesia (TD), we
have found that depression may be associated with a more severe variant.
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会议论文
BRAIN ELECTRICAL ACTIVITY MAPPING IN NEUROPSYCHIATRIC PATIENTS
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批准号:3968575
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项目类别:
-
资助金额:$0.0万
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财政年份:--
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负责人:C N KARSON
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依托单位:
CLINICAL PHENOMENA IN SCHIZOPHRENIA--QUANTIFICATION IN A EFFORT TO SUBTYPE
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批准号:4696522
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:C N KARSON
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依托单位:
CLINICAL PHENOMENA IN SCHIZOPHRENIA AND DEVELOPMENT OF NOVEL TREATMENTS
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批准号:3944820
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:C N KARSON
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依托单位:
BRAIN ELECTRICAL ACTIVITY MAPPING IN NEUROPSYCHIATRIC PATIENTS
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批准号:3944818
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:C N KARSON
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依托单位:
BLINK RATE IN NEUROPSYCHIATRIC DISORDERS
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批准号:4696521
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:C N KARSON
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依托单位:
ELECTRORETINOGRAPHY IN SCHIZOPHRENIA
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批准号:4696523
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项目类别:
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资助金额:$0.0万
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财政年份:--
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负责人:C N KARSON
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依托单位:
海外基金