thLongitudinal modelling of adiposity, its determinants and its health consequences across childhood and adolescence

肥胖症、其决定因素及其对儿童和青春期健康影响的纵向模型

基本信息

  • 批准号:
    G1002375/1
  • 负责人:
  • 金额:
    $ 54.48万
  • 依托单位:
  • 依托单位国家:
    英国
  • 项目类别:
    Fellowship
  • 财政年份:
    2011
  • 资助国家:
    英国
  • 起止时间:
    2011 至 无数据
  • 项目状态:
    已结题

项目摘要

Child obesity has become far more common in recent years, and is associated with health problems. This project looks at how obesity develops and changes over childhood and adolescence, how this is affected by changes in diet and physical activity, and how it relates to changes in blood pressure and other measures of health that are indicators of future heart disease risk. The project will also look at whether changes in early life can predict whether an individual is likely to be extremely obese when they are a young adult. Some obese people remain healthy despite being obese (e.g. they do not have higher risk of heart disease). This project will also look at whether changes in early life can predict which obese people will stay healthy. This project uses information from a study called ALSPAC, or ‘Children of the 90s‘. This started with over 14,000 pregnant women in Bristol in 1991/92. The mothers and their children have been followed ever since. I will also use information from ‘Born in Bradford‘ which is following 10,000 mothers and their children (5000 of European origin and 5000 of Pakistani origin) who were recruited when the mothers were pregnant between 2007-10.
近年来,儿童肥胖症变得越来越普遍,并与健康问题有关。该项目着眼于肥胖如何在儿童和青少年时期发展和变化,如何受到饮食和体育活动变化的影响,以及它如何与血压和其他健康指标的变化相关,这些指标是未来心脏病风险的指标。该项目还将研究早期生活的变化是否可以预测一个人在年轻时是否可能极度肥胖。一些肥胖的人尽管肥胖但仍然保持健康(例如,他们没有更高的心脏病风险)。该项目还将研究早期生活的变化是否可以预测哪些肥胖者将保持健康。该项目使用了一项名为ALSPAC或“90年代儿童”的研究的信息。1991/1992年在布里斯托,有14 000多名孕妇参加了这项工作。从那以后,母亲和孩子们一直被跟踪。我还将使用来自“出生在布拉德福德”的信息,该信息跟踪了10,000名母亲及其子女(5000名欧洲血统和5000名巴基斯坦血统),这些母亲在2007年至2010年期间怀孕时被招募。

项目成果

期刊论文数量(0)
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Laura D Howe其他文献

Using the Primary care Academic CollaboraTive to explore the characteristics and healthcare use of older housebound patients in England: protocol for a retrospective observational study and clinician survey (the CHiP study)
利用初级保健学术合作组织探索英格兰老年居家患者的特征和医疗保健使用情况:回顾性观察研究和临床医生调查方案(CHiP 研究)
  • DOI:
  • 发表时间:
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Elizabeth Winn;Madeleine Kissane;Sam Merriel;Thomas Brain;Victoria A Silverwood;Ishbel Orla Whitehead;Laura D Howe;Rupert A Payne;Polly Duncan
  • 通讯作者:
    Polly Duncan
fitness, fatness and the acute blood pressure
健身、肥胖和急性血压
  • DOI:
  • 发表时间:
    2021
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Zhengzheng Huang;Chloe M. Park;Nish Chaturvedi;Laura D Howe;James E Sharman;D. Alun;Hughes;M. Schultz
  • 通讯作者:
    M. Schultz
Adverse childhood experiences in firstborns and mental health risk and health-care use in siblings: a population-based birth cohort study of half a million children in England
长子的不良童年经历以及兄弟姐妹的心理健康风险和医疗保健使用情况:一项基于人群的英格兰 50 万儿童出生队列研究
  • DOI:
    10.1016/s2468-2667(24)00301-3
  • 发表时间:
    2025-02-01
  • 期刊:
  • 影响因子:
    25.200
  • 作者:
    Shabeer Syed;Laura D Howe;Rebecca E Lacey;Jessica Deighton;Muhammad Qummer ul Arfeen;Gene Feder;Ruth Gilbert
  • 通讯作者:
    Ruth Gilbert
Self-reported sleep in late pregnancy in relation to birth size and fetal distress: the E Moe, Māmā prospective cohort study
妊娠晚期自我报告的睡眠与出生大小和胎儿窘迫的关系:E Moe、Māmā 前瞻性队列研究
  • DOI:
  • 发表时间:
    2015
  • 期刊:
  • 影响因子:
    2.9
  • 作者:
    Laura D Howe;T. Signal;S. Paine;Bronwyn Sweeney;M. Priston;D. Muller;Kathy Lee;Mark Huthwaite;P. Gander
  • 通讯作者:
    P. Gander
Differences between brachial and aortic blood pressure in adolescence and their impact on classification of hypertension
青春期肱动脉血压和主动脉血压的差异及其对高血压分类的影响
  • DOI:
  • 发表时间:
    2023
  • 期刊:
  • 影响因子:
    0
  • 作者:
    Alun D. Hughes;George Davey Smith;Laura D Howe;Deborah A Lawlor;Siana Jones;Chloe M. Park;Nish Chaturvedi
  • 通讯作者:
    Nish Chaturvedi

Laura D Howe的其他文献

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{{ truncateString('Laura D Howe', 18)}}的其他基金

Early life adversity and trajectories of cardiometabolic health, cognitive function and physical function: improving understanding of the mechanisms a
生命早期的逆境和心脏代谢健康、认知功能和身体功能的轨迹:增进对机制的理解
  • 批准号:
    ES/M010317/1
  • 财政年份:
    2015
  • 资助金额:
    $ 54.48万
  • 项目类别:
    Research Grant
INTERpreting epigenetic signatures in STudies of Early Life Adversity (InterStELA)
解释早期生命逆境研究中的表观遗传特征 (InterStELA)
  • 批准号:
    ES/N000382/1
  • 财政年份:
    2015
  • 资助金额:
    $ 54.48万
  • 项目类别:
    Research Grant
Mediation analysis in life course epidemiology: methodological innovation and application to studies of obesity and cardiometabolic health
生命过程流行病学的中介分析:方法创新及其在肥胖和心脏代谢健康研究中的应用
  • 批准号:
    MR/M020894/1
  • 财政年份:
    2015
  • 资助金额:
    $ 54.48万
  • 项目类别:
    Fellowship
Early life adversity and trajectories of cardiometabolic health, cognitive function and physical function: improving understanding of the mechanisms and potential reversibility
生命早期的逆境和心脏代谢健康、认知功能和身体功能的轨迹:增进对机制和潜在可逆性的理解
  • 批准号:
    8797405
  • 财政年份:
    2014
  • 资助金额:
    $ 54.48万
  • 项目类别:

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