thLongitudinal modelling of adiposity, its determinants and its health consequences across childhood and adolescence

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Child obesity has become far more common in recent years, and is associated with health problems. This project looks at how obesity develops and changes over childhood and adolescence, how this is affected by changes in diet and physical activity, and how it relates to changes in blood pressure and other measures of health that are indicators of future heart disease risk. The project will also look at whether changes in early life can predict whether an individual is likely to be extremely obese when they are a young adult. Some obese people remain healthy despite being obese (e.g. they do not have higher risk of heart disease). This project will also look at whether changes in early life can predict which obese people will stay healthy. This project uses information from a study called ALSPAC, or ‘Children of the 90s‘. This started with over 14,000 pregnant women in Bristol in 1991/92. The mothers and their children have been followed ever since. I will also use information from ‘Born in Bradford‘ which is following 10,000 mothers and their children (5000 of European origin and 5000 of Pakistani origin) who were recruited when the mothers were pregnant between 2007-10.