thLongitudinal modelling of adiposity, its determinants and its health consequences across childhood and adolescence

肥胖症、其决定因素及其对儿童和青春期健康影响的纵向模型

• 批准号: G1002375/1
• 负责人: Laura D Howe
• 金额: $ 54.48万
• 依托单位: University of Bristol
• 依托单位国家: 英国
• 项目类别: Fellowship
• 财政年份: 2011
• 资助国家: 英国
• 起止时间: 2011 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=G1002375%2F1
• 关键词: thLongitudinal; modelling; adiposity; its; determinants

Child obesity has become far more common in recent years, and is associated with health problems. This project looks at how obesity develops and changes over childhood and adolescence, how this is affected by changes in diet and physical activity, and how it relates to changes in blood pressure and other measures of health that are indicators of future heart disease risk. The project will also look at whether changes in early life can predict whether an individual is likely to be extremely obese when they are a young adult. Some obese people remain healthy despite being obese (e.g. they do not have higher risk of heart disease). This project will also look at whether changes in early life can predict which obese people will stay healthy. This project uses information from a study called ALSPAC, or ‘Children of the 90s‘. This started with over 14,000 pregnant women in Bristol in 1991/92. The mothers and their children have been followed ever since. I will also use information from ‘Born in Bradford‘ which is following 10,000 mothers and their children (5000 of European origin and 5000 of Pakistani origin) who were recruited when the mothers were pregnant between 2007-10.

近年来，儿童肥胖症变得更加普遍，并与健康问题有关。这个项目着眼于肥胖是如何在儿童和青少年时期发展和变化的，它是如何受到饮食和体力活动变化的影响的，以及它与血压和其他健康指标的变化是如何关联的，这些指标是未来心脏病风险的指标。该项目还将研究早期生活的变化是否可以预测一个人在年轻时是否可能极度肥胖。一些肥胖的人尽管肥胖(例如，他们患心脏病的风险并不高)，但他们仍然健康。该项目还将研究早期生活的变化是否可以预测哪些肥胖者会保持健康。该项目使用了一项名为ALSPAC的研究中的信息，即“90年代的孩子”。这始于1991/92年布里斯托尔14,000多名孕妇。从那以后，这些母亲和她们的孩子一直被跟踪。我还将使用‘出生在布拉德福德’的信息，该网站跟踪了10,000名母亲及其子女(5,000名欧洲血统和5,000名巴基斯坦血统)，她们是在2007-10年间怀孕时被招募的。