Dissecting roles of High Mobility Group A1 (HMGA1) pathway in pancreatic adenocarcinoma progression through in vivo monitoring of cancer dynamics...

点击翻译按钮获取中文摘要

Pancreatic cancer is the deadliest of human cancers. Effective treatment and early detection strategies for this cancer is desperately needed. Our project aims to understand the process of pancreatic cancer progression, in the hope of identifying new ways to treat and detect this cancer. By focussing on the roles of high mobility group A1 (HMGA1) gene, we may identify novel pathways for rational therapy of pancreatic cancer. Our project may lead to the development of imaging-based early detection strategies.