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Developmental Clinical Studies - development of vitamin D therapy to prevent acute lung injury.

Developmental Clinical Studies - development of vitamin D therapy to prevent acute lung injury.
发育临床研究 - 开发维生素 D 疗法以预防急性肺损伤。
批准号：
G1100196/1
负责人：
David Thickett
金额：
$62.53万
依托单位：
University of Birmingham
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2012
资助国家：
英国
项目状态：
已结题
起止时间：
2012 至 --
来源：
https://gtr.ukri.org/projects?ref=G1100196%2F1
关键词：
DevelopmentalClinicalStudiesdevelopmentvitamin

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中文摘要
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英文摘要
The aim of this research is to develop vitamin D as a therapy to prevent acute lung injury. Acute lung injury ALI is a major cause of lung failure in critically ill patients. Most patients affected are of working age and survivors experience a significant reduction in health-related quality of life, with 46% unable to return to work within 12 months. Currently, apart from invasive protective ventilation, no therapy has been conclusively proven to reduce mortality or improve functional outcome in survivors. This represents a major unmet health need. By undertaking this research we will establish if simple and cheap replacement of vitamin D influences the development and severity of acute lung injury.
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会议论文
Does hospitalisation of older patients with severe community acquired pneumonia and sepsis lead to long term immunoparesis?
  • 批准号：
    MR/S002782/1
  • 项目类别：
    Research Grant
  • 资助金额：
    $66.85万
  • 财政年份：
    2019
  • 负责人：
    David Thickett
  • 依托单位：
    University of Birmingham
Hydroxysteroid Dehydrogenase activity and the vitamin D axis in acute lung injury - mechanistic and functional importance.
  • 批准号：
    MR/L002736/1
  • 项目类别：
    Research Grant
  • 资助金额：
    $44.2万
  • 财政年份：
    2014
  • 负责人：
    David Thickett
  • 依托单位：
    University of Birmingham
国内基金
海外基金
Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data