A PROGRAM IN BONE MARROW TRANSPLANTATION
A PROGRAM IN BONE MARROW TRANSPLANTATION
批准号:
3093046
负责人:
ROBERT P GALE
金额:
$98.54万
依托单位国家:
美国
项目类别:
财政年份:
1983
资助国家:
美国
项目状态:
已结题
起止时间:
1983-07-15 至 1987-05-31
中文摘要
在过去的九年里,加州大学洛杉矶分校的移植生物学部门一直在
参与一项持续的骨髓移植计划
再生障碍性贫血、白血病、癌症和
免疫缺陷疾病。这些患者中的许多人已经成为长期的
幸存者,但仍有相当多的问题需要解决,包括
预防移植物排斥反应、移植物抗宿主病(GVHD)、延迟
免疫重建和间质性肺炎。这份提案概述了
我们正在进行的三个主要计划领域的研究:(1)
骨髓移植;(3)移植中的间质性肺炎
收件人。这些研究包括对狗的临床前研究,以及
对照临床试验。拟议项目的目标是
骨髓移植在临床治疗中的应用进展
通过深入分析人类疾病移植的基本问题
动物生物学和适当的临床试验。
英文摘要
For the past nine years, the Transplantation Biology Unit at UCLA has been
involved in a continuing program of bone marrow transplantation in the
treatment of patients with aplastic anemia, leukemia, cancer, and
immunodeficiency diseases. Many of these patients have become long-term
survivors but considerable problems remain to be addressed including
prevention of graft rejection, graft-vs-host disease (GVHD), delay of
immune reconstitution and interstitial pneumonia. This proposal outlines
our ongoing studies in three major program areas: (1) the immunobiology of
marrow transplantation, and (3) interstitial pneumoia in transplant
recipients. These studies include preclinical studies in dogs, and
controlled clinical trials. The objective of the proposed project is to
continue progress in the application of bone marrow transplantation to
human disease by an in-depth analysis of basic problems of transplantation
biology in animals and by appropriate clinical trials.
期刊论文(0)
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会议论文
CONFERENCE ON BLOOD CELL AND BONE MARROW TRANSPLANTS
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批准号:2114824
-
项目类别:
-
资助金额:$0.7万
-
财政年份:1996
-
负责人:ROBERT P GALE
-
依托单位:
DIAGNOSIS OF LEUKEMIA (CML) ONCOGENE (C-ABL) EXPRESSION
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批准号:3176619
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项目类别:
-
资助金额:$7.45万
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财政年份:1985
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负责人:ROBERT P GALE
-
依托单位:
DIAGNOSIS OF LEUKEMIA (CML) ONCOGENE (C-ABL) EXPRESSION
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批准号:3176620
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项目类别:
-
资助金额:$9.94万
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财政年份:1985
-
负责人:ROBERT P GALE
-
依托单位:
DIAGNOSIS OF LEUKEMIA (CML) ONCOGENE (C-ABL) EXPRESSION
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批准号:3176617
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项目类别:
-
资助金额:$8.42万
-
财政年份:1985
-
负责人:ROBERT P GALE
-
依托单位:
A PROGRAM IN BONE MARROW TRANSPLANTATION
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批准号:3093047
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项目类别:
-
资助金额:$90.95万
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财政年份:1983
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负责人:ROBERT P GALE
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依托单位:
BONE MARROW TRANSPLANTATION--TRANSPLANTATION DONORS
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批准号:4703843
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项目类别:
-
资助金额:$0.0万
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财政年份:--
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负责人:ROBERT P GALE
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依托单位:
ACUTE MYELOGENOUS LEUKEMIA
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批准号:4690998
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项目类别:
-
资助金额:$0.0万
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财政年份:--
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负责人:ROBERT P GALE
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依托单位:
CHRONIC MYELOGENOUS LEUKEMIA
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批准号:4690999
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项目类别:
-
资助金额:$0.0万
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财政年份:--
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负责人:ROBERT P GALE
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依托单位:
BIOSTATISTICS CORE
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批准号:4691005
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项目类别:
-
资助金额:$0.0万
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财政年份:--
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负责人:ROBERT P GALE
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依托单位:
海外基金