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HUMAN LUNG CARCINOMA/BRONCHIAL EPITHELIAL CELL HYBRID GENETICS

HUMAN LUNG CARCINOMA/BRONCHIAL EPITHELIAL CELL HYBRID GENETICS
人类肺癌/支气管上皮细胞混合遗传学
批准号：
4692376
负责人：
E W GABRIELSON
金额：
$0.0万
依托单位：
DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/4692376
关键词：
bronchus cancer registry /resource carcinoma cell population study gene expression human tissue hybrid cells karyotype lung neoplasms neoplasm /cancer genetics neoplasm /cancer remission /regression neoplastic cell respiratory epithelium tissue /cell culture

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中文摘要
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英文摘要
Genetic changes related to carcinogenesis are being studied using hybrids of human lung carcinoma cells with normal human bronchial epithelial cells. Initial studies suggest that a limited population doubling potential (mortality) is a dominant genetic trait in hybrid cells. Other hybrid lines have been isolated and are being characterized for doubling potential, karyotype and tumorigenicity in athymic nude mice.
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CYTOPATHOLOGY OF ASBESTOS AND OTHER FIBERS ON HUMAN LUNG CELLS IN CULTURE