课题基金 / 基金详情

CYTOPATHOLOGY OF ASBESTOS AND OTHER FIBERS ON HUMAN LUNG CELLS IN CULTURE

CYTOPATHOLOGY OF ASBESTOS AND OTHER FIBERS ON HUMAN LUNG CELLS IN CULTURE
石棉和其他纤维对培养的人肺细胞的细胞病理学
批准号：
4692385
负责人：
E W GABRIELSON
金额：
$0.0万
依托单位：
DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/4692385
关键词：
X ray crystallography asbestos bronchus carcinogen testing cell population study cell type cellular oncology chemical carcinogen chemical carcinogenesis chromosome disorders cytodiagnosis cytotoxicity electron microscopy electron probe spectrometry environmental toxicology fibroblasts glass histopathology human tissue neoplasm /cancer diagnosis neoplasm /cancer genetics particle phagocytosis phase contrast microscopy physical chemical interaction respiratory epithelium tissue /cell culture

项目摘要

项目成果

E W GABRIELSON的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
Our laboratory is studying the cytopathology of asbestos fibers on human bronchial epithelial cells, human mesothelial cells and human fibroblasts in culture. Electron microscopy studies have demonstrated phagocytosis of the fibers and phase-microscopy of metaphase spreads reveal frequent attachment of the fibers to the chromosomes. Investigations regarding the mechanism of asbestos carcinogenesis suggest that oxygen radicals are probably not important intermediates. Further studies have examined the cytotoxicity of synthetic fibers, i.e., glass and carbon-graphite, on human mesothelial cell cultures.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
HUMAN LUNG CARCINOMA/BRONCHIAL EPITHELIAL CELL HYBRID GENETICS
海外基金