Realising Unmet Potential in Translational Medical Science at Durham

实现达勒姆转化医学科学中未满足的潜力

• 批准号: MC_PC_17157
• 负责人: Claire Warwick
• 金额: $ 37.59万
• 依托单位: Durham University
• 依托单位国家: 英国
• 项目类别: Intramural
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MC_PC_17157
• 关键词: Realising; Unmet; Potential; Translational; Medical

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

目前GtR中并没有所有资助研究的摘要。这通常是因为在提交提案时不需要摘要，但也可能是因为摘要中包含个人详细信息等敏感信息。

项目成果

Antileishmanial Chemotherapy through Clemastine Fumarate Mediated Inhibition of the Leishmania Inositol Phosphorylceramide Synthase.

• DOI: 10.1021/acsinfecdis.0c00546
• 发表时间: 2021-01-08
• 期刊: ACS infectious diseases
• 影响因子: 5.3
• 作者: Mina JGM;Charlton RL;Alpizar-Sosa E;Escrivani DO;Brown C;Alqaisi A;Borsodi MPG;Figueiredo CP;de Lima EV;Dickie EA;Wei W;Coutinho-Silva R;Merritt A;Smith TK;Barrett MP;Rossi-Bergmann B;Denny PW;Steel PG
• 通讯作者: Steel PG

Genome deletions to overcome the directed loss of gene function in Leishmania.

• DOI: 10.3389/fcimb.2022.988688
• 发表时间: 2022
• 期刊: Frontiers in cellular and infection microbiology
• 影响因子: 5.7

Protecting Group-Controlled Remote Regioselective Electrophilic Aromatic Halogenation Reactions

• DOI: 10.1021/acs.joc.9b03322
• 发表时间: 2020-06-05
• 期刊: JOURNAL OF ORGANIC CHEMISTRY
• 影响因子: 3.6
• 作者: Brittain, William D. G.;Cobb, Steven L.
• 通讯作者: Cobb, Steven L.

Synthesis of complex unnatural fluorine-containing amino acids.

• DOI: 10.1016/j.jfluchem.2020.109630
• 发表时间: 2020-11
• 期刊: Journal of fluorine chemistry
• 影响因子: 1.9
• 作者: Brittain WDG;Lloyd CM;Cobb SL
• 通讯作者: Cobb SL

Amphotericin B resistance in Leishmania mexicana: Alterations to sterol metabolism and oxidative stress response.

• DOI: 10.1371/journal.pntd.0010779
• 发表时间: 2022-09
• 期刊: PLoS neglected tropical diseases
• 影响因子: 3.8