COVID-19 National DiagnOstic Research and Evaluation Platform (CONDOR)

COVID-19 国家诊断研究和评估平台 (CONDOR)

• 批准号: MC_PC_20008
• 负责人: Richard Body
• 金额: $ 74.84万
• 依托单位: University of Manchester
• 依托单位国家: 英国
• 项目类别: Intramural
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MC_PC_20008
• 关键词: COVID; 19; National; DiagnOstic; Research

A key part of our response to the COVID-19 pandemic is to accurately find out who is infected. Getting rapid answers when patients are first seen ensures that we can give the best care, reducing the chance of others catching the infection. In community settings, we can take steps to isolate infected people and trace their contacts. Companies are developing new tests both to detect SARS-CoV-2 (the virus causing COVID-19) and to find out if someone is already immune to the virus. It is crucial that these tests do not miss infections, or whether people really are immune. We need ways torapidly assess whether these new tests are accurate enough to be used in the NHS. Todo this we need to know how tests work in different settings, including the community,hospitals and care homes, and we must use high quality methods to evaluate them.We will set up a national network of experts in evaluating diagnostic tests to assess theaccuracy of these new tests. We will prioritise tests that are likely to give the bestimprovements in patient care by working with government bodies. We will ask patients totake part if they have symptoms that could have been caused by COVID-19. We will takeblood samples and swabs from the nose/throat, and we will compare the results of newtests to the results of proven methods to diagnose COVID-19. This will allow us to find outwhich tests are best to use in the NHS.

我们应对COVID-19大流行的关键部分是准确找出谁被感染。在病人第一次就诊时迅速得到答复，确保我们能够提供最好的护理，减少其他人感染的机会。在社区环境中，我们可以采取措施隔离感染者并追踪他们的接触者。公司正在开发新的检测方法，以检测SARS-CoV-2（引起COVID-19的病毒），并确定是否有人已经对该病毒免疫。至关重要的是，这些测试不会错过感染，或者人们是否真的有免疫力。我们需要快速评估这些新的测试是否足够准确，可以用于NHS。为此，我们需要了解测试在不同环境中的工作方式，包括社区、医院和疗养院，并且我们必须使用高质量的方法来评估它们。我们将建立一个评估诊断测试的全国专家网络，以评估这些新测试的准确性。我们将与政府机构合作，优先考虑可能改善患者护理的测试。如果患者出现可能由COVID-19引起的症状，我们将要求他们参加。我们将从鼻/喉采集血液样本和拭子，并将新检测的结果与已证实的COVID-19诊断方法的结果进行比较。这将使我们能够找出哪些测试是最好的使用在国民保健服务。