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Non-hospitalised Children & young people (CYP) with Long Covid (The CLoCk Study)

非住院儿童

基本信息

批准号：
MC_PC_20052
负责人：
金额：
$ 119.13万
依托单位：
Great Ormond Street Hospital
依托单位国家：
英国
项目类别：
Intramural
财政年份：
2021
资助国家：
英国
起止时间：
2021 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=MC_PC_20052
关键词：
Non hospitalised Children young people

项目摘要

a. aim(s) of the research: It seems that some children and young people (CYP) remain ill for a long time after infection with COVID virus. They are said to have ‘long COVID’. Something similar can follow a common childhood infection called glandular fever. Doctors don’t know how to diagnose long COVID, how common it is or how long it goes on for. There is no simple test for long COVID. We need to know more about it if we want to treat it. b. background to the research: Little is known about long COVID in adults or CYP. Risk factors for worse COVID in CYP include obesity, pre-existing diseases, learning disabilities, diseases of the brain, mental health problems and coming from an ethnic minority. The CYP likely to be most at risk of long COVID are teenagers who are more at risk of persistent fatigue and mental health problems after other viral infections. c. design and methods used: We will approach 30,000 CYP, half of whom we know had COVID. We expect 6,000 to agree to help us and we will ask them whether they still have physical or mental problems at 3, 6,12 and 24 months afterwards. We can compare the 3,000 responders who had a positive COVID test with the 3,000 responders who didn’t test positive. We can then agree on what is a medical diagnosis of long COVID and how we might treat it. d. patient and public involvement: (PPI): We will have a paid PPI lead who will ensure co-production with carers and CYP. We will also use some funds to encourage busy carers and CYP to give their valuable time to complete the survey s.e. Complete transparency: We will share all our results ASAP for free with anyone who wants to see them, especially the CYP who take part.

a.研究的目的：似乎有些儿童和年轻人在感染COVID病毒后很长一段时间内仍然生病。他们被称为“长COVID”。类似的情况也会发生在一种叫做腺热的常见儿童感染之后。医生不知道如何诊断长期COVID，它有多常见或持续多久。长期的COVID没有简单的测试。如果我们想治疗的话我们需要更多的了解。B。研究背景：对成年人或老年人的长期COVID知之甚少。在中国，导致新冠肺炎恶化的风险因素包括肥胖、既往疾病、学习障碍、脑部疾病、心理健康问题和来自少数民族。最有可能长期感染新冠病毒的人群是青少年，他们在感染其他病毒后更有可能出现持续疲劳和心理健康问题。C.使用的设计和方法：我们将接触30，000名CYP，其中一半我们知道患有COVID。我们预计会有6，000人同意帮助我们，我们会在3个月、6个月、12个月和24个月后询问他们是否仍然有身体或精神问题。我们可以将3,000名COVID检测呈阳性的应答者与3,000名未检测呈阳性的应答者进行比较。然后，我们可以就什么是长期COVID的医学诊断以及我们如何治疗它达成一致。患者和公众参与：（PPI）：我们将有一个付费的PPI领导，他将确保与护理人员和患者共同制作。我们亦会拨出部分款项，鼓励忙碌的护老者及照顾者抽出宝贵的时间完成调查。完全透明：我们将尽快免费与任何想看到结果的人分享我们的所有结果，特别是参与的专家。