Supplementary funding to support the extension of the EDCTP-funded MMVC
Supplementary funding to support the extension of the EDCTP-funded MMVC
批准号:
MC_PC_23003
负责人:
金额:
$65.87万
依托单位国家:
英国
项目类别:
Intramural
财政年份:
2023
资助国家:
英国
项目状态:
未结题
起止时间:
2023 至 --
中文摘要
补充资金,以支持扩展由EDCTP资助的“多阶段疟疾疫苗联盟:针对寄生虫生命周期所有四个阶段的疟疾疫苗的现场药效测试”,由牛津大学禤浩焯·希尔教授主持。由于新冠肺炎疫情的负面影响,研究被推迟。该项目将开发第一个多阶段疫苗,旨在针对恶性疟原虫生命周期的多个阶段,包括子孢子、肝脏、血液和蚊子阶段。多阶段疟疾疫苗的每一种成分都将在非洲进行临床试验,以确保疫苗是安全的,刺激免疫反应,在我们的一些研究中,在预防疟疾方面是有效的。网址:https://www.jenner.ac.uk/mmvc“
英文摘要
"Supplementary funding to support the extension of the EDCTP-funded “Multi-Stage Malaria Vaccine Consortium: field efficacy testing of a malaria vaccine targeting all four stages of the parasite’s life-cycle (MMVC)” held by Professor Adrian Hill (University of Oxford). Study delayed due to the negative impacts of the Covid-19 pandemic. In this project will develop the first multi-stage vaccine designed to target multiple stages of the P. falciparum malaria parasite’s life-cycle, including the sporozoite, liver, blood and mosquito stages. Each component of the multi-stage malaria vaccine will be tested in clinical trials in Africa to ensure the vaccines are safe, stimulate an immune response, and in some of our studies, are effective in preventing malaria. Website: https://www.jenner.ac.uk/mmvc"
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