Enabling technologies
支持技术
基本信息
- 批准号:MC_UU_00014/5
- 负责人:
- 金额:$ 427.56万
- 依托单位:
- 依托单位国家:英国
- 项目类别:Intramural
- 财政年份:2018
- 资助国家:英国
- 起止时间:2018 至 无数据
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The Enabling Technologies programme consists of a number of core facilities that provide critical technologies and equipment to scientists in the MDU and it is crucial its success. Because metabolic disease affects the entire body, it is vital to study these diseases whole animals. Our model of choice is the mouse. The Disease Model Core provides facilities for the measurement of the amount of fat and muscle in an animal’s body, how much and what type of food is eaten, and how much energy is burnt, through either metabolism, heat production, or exercise. It also provides facilities for examining isolated cells, tissues and organs. At the other end of the size spectrum, the Genomics/Transcriptomics Core enables scientists to study the sub-microscopic world of genes and how they function and are turned into proteins and the Core Biochemistry Assay Lab measures hormones and other molecules in blood.
使能技术方案包括一些核心设施,为MDU的科学家提供关键技术和设备,其成功至关重要。由于代谢性疾病影响整个身体,因此研究整个动物的这些疾病至关重要。我们选择的模型是老鼠。疾病模型核心提供了测量动物体内脂肪和肌肉量的设施,吃了多少和什么类型的食物,以及通过代谢,产热或运动燃烧了多少能量。它还提供了检查分离的细胞、组织和器官的设施。在尺寸范围的另一端,基因组学/转录组学核心使科学家能够研究基因的亚微观世界以及它们如何发挥作用并转化为蛋白质,核心生物化学分析实验室测量血液中的激素和其他分子。
项目成果
期刊论文数量(10)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
The early life environment influences trajectory of post-partum weight loss
早期生活环境影响产后减肥轨迹
- DOI:10.17863/cam.35742
- 发表时间:2019
- 期刊:
- 影响因子:0
- 作者:Aiken C
- 通讯作者:Aiken C
Early life environment influences the trajectory of post-partum weight loss in adult female rats.
早期生活环境影响成年雌性大鼠产后体重减轻的轨迹。
- DOI:10.1016/j.rbmo.2018.12.002
- 发表时间:2019
- 期刊:
- 影响因子:4
- 作者:Aiken CE
- 通讯作者:Aiken CE
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Giles Yeo其他文献
XXVIIth Annual Meeting of the European Chemoreception Research
第二十七届欧洲化学感受研究年会
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
Charles Spence;Janice Wang1;J. Youssef;Giles Yeo;Richard Benton;Julie Mennella;Vanessa Ruta;W. Meyerhof;Anja Voigt;Sandra Hübner;Kristina Lossow;Jonas Töle;Antje Stolzenburg;A. Brockhoff;K. Blank;Ulrich Boehm;M. Behrens;M. Gibbs;Alexander Horsfall;C. O’Flynn;Neil Desforges;Oliver Forman;M. Winnig;N. Holliday;S. McGrane;Darren W. Logan;C. Uytingco;Jeffrey R Martens;H. Loos;Constanze Sharapa;Sébastien Doucet;Andrea Buettner;B. Schaal;Emre Yaksi;F. Kermen;Xiaoyang Serene;Hu;Kentaro Ikegami;Marcelo Zapata;Natasha Vaidya;Matthew Do;C. March;Hiroaki Matsunami;A. Kernerová;L. Nováková;Jitka Fialová;Markéta Sobotková;Jan Havl í č ek - 通讯作者:
Jan Havl í č ek
01-P010 Prader–Willi Syndrome and small nucleolar RNAs
- DOI:
10.1016/j.mod.2009.06.011 - 发表时间:
2009-08-01 - 期刊:
- 影响因子:
- 作者:
Carolin Purmann;Giles Yeo;Sadaf Farooqi;Stephen O’Rahilly - 通讯作者:
Stephen O’Rahilly
The implications of defining obesity as a disease: a report from the Association for the Study of Obesity 2021 annual conference
将肥胖定义为一种疾病的影响:来自肥胖研究协会 2021 年年会的报告
- DOI:
10.1016/j.eclinm.2023.101962 - 发表时间:
2023-04-01 - 期刊:
- 影响因子:10.000
- 作者:
Migena Luli;Giles Yeo;Emma Farrell;Jane Ogden;Helen Parretti;Emma Frew;Stephen Bevan;Adrian Brown;Jennifer Logue;Vinod Menon;Nadya Isack;Michael Lean;Chris McEwan;Paul Gately;Simon Williams;Nerys Astbury;Maria Bryant;Kenneth Clare;Georgios K. Dimitriadis;Graham Finlayson;Alexander Dimitri Miras - 通讯作者:
Alexander Dimitri Miras
Giles Yeo的其他文献
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{{ truncateString('Giles Yeo', 18)}}的其他基金
Mapping the neuronal functional architecture underlying appetite control in humans at the extremes of bodyweight
绘制极端体重下人类食欲控制的神经元功能结构
- 批准号:
BB/X014207/1 - 财政年份:2024
- 资助金额:
$ 427.56万 - 项目类别:
Research Grant
Molecular characterization in human neurons of genes associated with severe obesity identified from consanguineous pedigrees.
从近亲谱系中鉴定出的与严重肥胖相关的人类神经元基因的分子特征。
- 批准号:
MR/S026193/1 - 财政年份:2019
- 资助金额:
$ 427.56万 - 项目类别:
Research Grant
Mapping the human hypothalamic functional architecture underlying food intake control
绘制食物摄入控制背后的人类下丘脑功能结构
- 批准号:
BB/S017593/1 - 财政年份:2019
- 资助金额:
$ 427.56万 - 项目类别:
Research Grant
Mechanisms in Disorders of Energy Balance
能量平衡紊乱的机制
- 批准号:
MC_UU_00014/1 - 财政年份:2018
- 资助金额:
$ 427.56万 - 项目类别:
Intramural
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