REU Site: Enabling Technologies and New REU Approaches to Engineer Complex Tissues

REU 网站：工程复杂组织的支持技术和 REU 新方法

• 批准号: 2243993
• 负责人: Anthony Atala
• 金额: $ 38.74万
• 依托单位: Wake Forest University School of Medicine
• 依托单位国家: 美国
• 项目类别: Standard Grant
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-10-01 至 2026-09-30
• 项目状态: 未结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=2243993&HistoricalAwards=false
• 关键词: REU; Site; Enabling; Technologies; New

This three-year renewal REU Site, Enabling Technologies and New REU Approaches to Engineer Complex Tissues, will engage diverse cohorts of 10 undergraduate students each summer in highly collaborative, team-based 10-week multidisciplinary research projects in regenerative medicine at the Wake Forest Institute for Regenerative Medicine (WFIRM). A challenge facing the regenerative medicine field and the broader STEM disciplines is developing the next generation of skilled bioengineers. Regenerative medicine is a multidisciplinary field involving engineering and other STEM disciplines. Students will focus on learning about enabling technologies and biomanufacturing approaches in regenerative medicine and the emerging field of biofabrication. The REU experience is supplemented with additional program activities and education on the research process, hands-on instrumentation, workshops on bioethics, responsible conduct of research, effective oral and written communication, professional development, networking, and career opportunities topics. WFIRM has been at the forefront in RM research for nearly two decades and is an internationally recognized center of excellence in research and training.This renewal REU Site, Enabling Technologies and New REU Approaches to Engineer Complex Tissues, will engage diverse cohorts of 10 undergraduate students each summer for three years in highly collaborative, team-based 10-week multidisciplinary research projects in regenerative medicine (RM) at the Wake Forest Institute for Regenerative Medicine (WFIRM). Students will learn about enabling technologies and biomanufacturing approaches and the emerging field of biofabrication. This REU, emphasizing RM enabling technologies and biomanufacturing, is focused on two convergent research areas: 1) enabling technologies biomanufacturing and biofabrication (3D bioprinting, bioreactors, encapsulation and bioengineering of multi-cellular tissue constructs (organoids/body-on-a-chip) as modeling platforms and 2) stem cells/gene editing as applied to engineering one or more tissue/organ application. The REU experience is supplemented with additional program elements and education on the research process, hands-on instrumentation, workshops on bioethics, responsible conduct of research, effective oral and written communication, professional development, networking, and career opportunities topics. Also included is an introductory course to familiarize students with the essentials of the regenerative medicine field and seminars on “hot” topics in the field. All students will present their research findings throughout the summer and at a final research day symposium. WFIRM has been at the forefront in RM research for nearly two decades and is an internationally recognized center of excellence in research and training.This award reflects NSF's statutory mission and has been deemed worthy of support through evaluation using the Foundation's intellectual merit and broader impacts review criteria.

这个为期三年的更新REU网站，促进技术和新的REU方法来设计复杂组织，每年夏天将在Wake Wake Forest Institute in Wake Forest Institute for Regenerative Medicine（WFIRM）的高度协作，基于团队的10周多学科研究项目中，参与高度协作，基于团队的10周多学科研究项目的潜水员。再生医学领域和更广泛的STEM学科面临的挑战是发展下一代熟练的生物工程师。再生医学是一个涉及工程和其他学科的多学科领域。学生将专注于学习再生医学中的技术和生物制造方法以及生物制造的新兴领域。 REU的经验补充了有关研究过程，动手仪器，有关生物伦理学，负责任的研究，有效的口头和书面交流，专业发展，网络和职业机会主题的其他计划活动和教育。 WFIRM在RM研究中一直处于最前沿已有近二十年的历史，并且是一个国际公认的研究和培训卓越中心。这次更新的REU站点，使技术和新的REU方法能够为工程师的复杂组织提供新的REU方法，每年夏天的10年夏季在高度协作，基于团队的研究项目中，将吸引10个周夏季的多年培训项目（REM）的多个户外研究（RMISTIDIAL ITROUTTION ITROUTTION ITROUTTION ITROUTTION ITROUTTOR INTERKITION）（RMISTIRATION MELIDERIDIAL）（RMISTIRATY）。再生医学（WFIRM）。学生将了解启用技术和生物制造方法以及生物制造的新兴领域。这种强调RM启用技术和生物制造的REU集中在两个收敛研究领域上：1）使技术能够生物制造和生物制造（3D生物打印，生物反应器，生物反应器，封装和生物工程以及多核心组织构造的多种细胞/构造）（造型）和2个模型），以及2个模型）（2）或更多组织/器官。 REU的经验补充了有关研究过程，动手仪器，生物伦理学，负责任的研究，有效的口头和书面交流，专业发展，网络和职业机会主题的其他计划要素和教育。还包括一门介绍课程，使学生熟悉再生医学领域的基本要素和有关该领域“热”主题的半岛。所有学生将在整个夏季和最后一项研究日研讨会上介绍他们的研究结果。 WFIRM在RM研究中一直处于最前沿已有近二十年的历史，并且是国际公认的研究和培训卓越中心。该奖项反映了NSF的法定任务，并通过评估该基金会的知识分子优点和更广泛的影响来审查标准。