Determining age-specific reference intervals for pathology tests in children using normative data collected in multiple paediatric centres in Victoria, Australia

参考区间是一个重要的临床评估工具，由95%的人群所在的范围来定义。由于血容量不足、生物标志物随年龄的变化、确定参考间隔的仪器和统计方法的不同，儿科参考间隔的构建过程是复杂的。为了解决这些差距，该项目将为30个生化生物标志物确定特定年龄的儿科参考区间。

Reference interval is an important clinical assessment tool defined by a rage within which 95% of the population fall. The process of constructing paediatric reference intervals are complex due the inadequate blood volume, changes in biomarker with age, variation due to instruments and statistical methods used for determining reference intervals. Addressing these gaps, this project will determine age-specific paediatric reference intervals for 30 biochemistry biomarkers.