Determining age-specific reference intervals for pathology tests in children using normative data collected in multiple paediatric centres in Victoria, Australia

使用澳大利亚维多利亚州多个儿科中心收集的规范数据确定儿童病理学测试的特定年龄参考区间

• 批准号: nhmrc : GNT1168363
• 金额: $ 3.23万
• 依托单位国家: 澳大利亚
• 项目类别: Postgraduate Scholarships
• 财政年份: 2019
• 资助国家: 澳大利亚
• 起止时间: 2019-01-01 至 无数据
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/determining-age-specific-victoria-australia/1379457
• 关键词: Determining; age; specific; reference; intervals

Reference interval is an important clinical assessment tool defined by a rage within which 95% of the population fall. The process of constructing paediatric reference intervals are complex due the inadequate blood volume, changes in biomarker with age, variation due to instruments and statistical methods used for determining reference intervals. Addressing these gaps, this project will determine age-specific paediatric reference intervals for 30 biochemistry biomarkers.

参考区间是一个重要的临床评估工具，由95%的人群所处的范围定义。由于血容量不足、生物标志物随年龄的变化、用于确定参考区间的仪器和统计方法的变化，构建儿科参考区间的过程很复杂。为了解决这些差距，本项目将确定30种生物化学生物标志物的年龄特异性儿科参考区间。