Active Assistance for Psychological Therapy (Actissist): Software to improve access and adherence to CBT targeting key relapse indicators in psychosis

心理治疗主动援助 (Actissist)：用于改善 CBT 的获取和依从性的软件，针对精神病的关键复发指标

• 批准号: MR/L005301/1
• 负责人: Sandra Bucci
• 金额: $ 59.35万
• 依托单位: University of Manchester
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2014
• 资助国家: 英国
• 起止时间: 2014 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=MR%2FL005301%2F1
• 关键词: Active; Assistance; Psychological; Therapy; Actissist

Serious mental health problems such as schizophrenia affect 24 million people worldwide. Schizophrenia is the most serious form of psychosis. Psychosis is a general term that describes a change in people's behaviour, thinking and perception. Psychosis affects people's ability to socialise, work and carry out the tasks of daily life, and usually begins in early adulthood. First episode psychosis is the first time someone experiences these changes. The period following a first episode of psychosis is critical in the long-term course of illness development. This is because the majority of people relapse, or experience more than one episode of psychosis. This makes the early phase of psychosis an important time to deliver treatment, because the longer the delay in treating psychosis, the worse the illness becomes. There is evidence that a talking therapy ('cognitive behaviour therapy' or CBT), as well as medication, can help reduce symptoms of psychosis further. Unfortunately, only 1 in 10 of those who could benefit from CBT have access to this treatment. This is for a variety of reasons, including a shortage of trained staff and pressure on health service resources. Even when people are offered CBT, they often don't receive it until late in their illness. In recent years, smartphones have become very popular. Smartphones are able to run advanced software applications, called 'apps'. Some healthcare treatments have already been successfully delivered using smartphone 'apps'.This study aims to develop and test the possible benefits of a CBT 'app' in the early stages of psychosis. Our goal is to make helpful treatments such as CBT more accessible. By doing this, we hope to reduce the number of psychotic episodes people experience, or at least keep these to a minimum. This is a proof of concept study. This means that we will provide 24 people with a CBT smartphone 'app', and 12 people with a smartphone 'app' designed to simply monitor psychosis and other symptoms. Which treatment people get will be randomly determined so that the treatments can be compared in similar groups of people. We expect the CBT 'app' will bring improvements in quality of life, social interactions and other important factors. We hope to gain a greater understanding of the possible benefits to delivering helpful treatments in the form of a mobile phone 'app'. We are also interested to see whether people like using the CBT 'app'. Our CBT 'app' will make helpful therapies more accessible for people with lived experience of psychosis. We will do this by translating CBT into a user-friendly 'app' that will be delivered through a familiar device (mobile phone) that people, especially young people, enjoy using. By doing this, we hope that we can help people notice if they are becoming unwell at an earlier point than if they relied on attending a mental health service. We hope that this will improve people's daily lives and keep them out of hospital. This study will provide patients, services and commissioners with information about different ways people can access healthcare. We would like to make helpful therapies widely available so more people feel empowered to make informed choices about their health care. Our 'app' has the potential to transform community care for people with serious mental illness with personalised self-management of symptoms and therapy.

精神分裂症等严重的精神健康问题影响着全世界2400万人。精神分裂症是最严重的精神病。精神病是一个通用术语，描述了人们的行为，思维和感知的变化。精神病影响人们社交、工作和执行日常生活任务的能力，通常始于成年早期。第一次精神病发作是第一次有人经历这些变化。第一次精神病发作后的时期在疾病发展的长期过程中至关重要。这是因为大多数人会复发，或者经历不止一次精神病发作。这使得精神病的早期阶段成为提供治疗的重要时间，因为治疗精神病的时间越长，病情就越严重。有证据表明，谈话疗法（“认知行为疗法”或CBT）以及药物治疗可以帮助进一步减轻精神病的症状。不幸的是，只有十分之一的人可以从CBT中受益，可以获得这种治疗。这是由于各种原因，包括缺乏训练有素的工作人员和对保健服务资源的压力。即使人们被提供CBT，他们也经常直到疾病晚期才接受它。近年来，智能手机变得非常流行。智能手机能够运行高级软件应用程序，称为“应用程序”。一些医疗保健治疗已经成功地使用智能手机“应用程序”提供。这项研究旨在开发和测试CBT“应用程序”在精神病早期阶段的可能益处。我们的目标是使CBT等有用的治疗更容易获得。通过这样做，我们希望减少人们经历的精神病发作的数量，或者至少将其保持在最低限度。这是一项概念验证研究。这意味着我们将为24人提供CBT智能手机“应用程序”，并为12人提供智能手机“应用程序”，旨在简单地监测精神病和其他症状。人们得到的治疗将是随机决定的，这样就可以在类似的人群中进行比较。我们预计CBT“应用程序”将带来生活质量，社交互动和其他重要因素的改善。我们希望能够更好地了解以移动的手机“应用程序”的形式提供有益治疗的可能好处。我们也有兴趣看看人们是否喜欢使用CBT“应用程序”。我们的CBT“应用程序”将使有精神病生活经历的人更容易获得有用的治疗。我们将通过将CBT转化为用户友好的“应用程序”来实现这一目标，该应用程序将通过人们，特别是年轻人喜欢使用的熟悉设备（移动的手机）提供。通过这样做，我们希望我们可以帮助人们注意到，如果他们变得不舒服，在一个较早的点，如果他们依赖于参加心理健康服务。我们希望这将改善人们的日常生活，使他们远离医院。这项研究将为患者，服务和专员提供有关人们获得医疗保健的不同方式的信息。我们希望广泛提供有用的治疗方法，让更多的人感到有能力对他们的医疗保健做出明智的选择。我们的“应用程序”有可能通过症状和治疗的个性化自我管理来改变严重精神疾病患者的社区护理。

项目成果

Using mobile technology to deliver a cognitive behaviour therapy-informed intervention in early psychosis (Actissist): study protocol for a randomised controlled trial.

• DOI: 10.1186/s13063-015-0943-3
• 发表时间: 2015-09-10
• 期刊: Trials
• 影响因子: 2.5
• 作者: Bucci S;Barrowclough C;Ainsworth J;Morris R;Berry K;Machin M;Emsley R;Lewis S;Edge D;Buchan I;Haddock G
• 通讯作者: Haddock G

Early Psychosis Service User Views on Digital Technology: Qualitative Analysis.

• DOI: 10.2196/10091
• 发表时间: 2018-10-31
• 期刊: JMIR mental health
• 影响因子: 5.2
• 作者: Bucci S;Morris R;Berry K;Berry N;Haddock G;Barrowclough C;Lewis S;Edge D
• 通讯作者: Edge D

Assessing Therapeutic Alliance in the Context of mHealth Interventions for Mental Health Problems: Development of the Mobile Agnew Relationship Measure (mARM) Questionnaire.

• DOI: 10.2196/jmir.8252
• 发表时间: 2018-04-19
• 期刊: Journal of medical Internet research
• 影响因子: 7.4
• 作者: Berry K;Salter A;Morris R;James S;Bucci S
• 通讯作者: Bucci S

Assessing Therapeutic Alliance in the Context of mHealth Interventions for Mental Health Problems: Development of the Mobile Agnew Relationship Measure (mARM) Questionnaire (Preprint)

在心理健康问题的移动医疗干预背景下评估治疗联盟：制定移动 Agnew 关系测量 (mARM) 调查问卷（预印本）

• DOI: 10.2196/preprints.8252
• 发表时间: 2017
• 作者: Berry K

Actissist: Proof-of-Concept Trial of a Theory-Driven Digital Intervention for Psychosis.

• DOI: 10.1093/schbul/sby032
• 发表时间: 2018-08-20
• 期刊: Schizophrenia bulletin
• 影响因子: 6.6
• 作者: Bucci S;Barrowclough C;Ainsworth J;Machin M;Morris R;Berry K;Emsley R;Lewis S;Edge D;Buchan I;Haddock G
• 通讯作者: Haddock G