HIGH VS LOW DOSE OF D-PENICILLAMINE IN EARLY SYSTEMIC SCLEROSIS

这是一项多中心、双盲、安慰剂对照研究 确定低剂量(每隔一天125毫克)与高剂量的效果 D-青霉胺1000 mg/d治疗全身性青霉病 (弥漫性)18个月以下的系统性硬化症。伊利诺伊大学 科罗拉多州健康科学中心分部完成了他们的一部分 研究12-30-95。已从关节炎基金会获得资金。 这将使我们能够追踪参与这一活动的患者 在离开D-青霉胺一年和两年后学习 学习。

This is a multicenter, double blind, placebo controlled study to determine the effect of low dose (125 mg every other day) vs high dose (1000 mg per day) of D-penicillamine on patients with generalized (diffuse) systemic sclerosis of less than 18 months. The University of Colorado Health Sciences Center Section completed their part of this study 12-30-95. Funding has been obtained from the arthritis foundation that will allow us to follow up the patients that participated in this study at one and two years after their departure from the D-penicillamine study.