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1,25 DIHYDROXY D3 ON GLUCOSE METABOLISM WITH NEPHROTIC PROTEINURIA

1,25 DIHYDROXY D3 ON GLUCOSE METABOLISM WITH NEPHROTIC PROTEINURIA
1,25 二羟基 D3 对肾病蛋白尿葡萄糖代谢的影响
批准号：
5218893
负责人：
ROBERT H MAK
金额：
$0.0万
依托单位：
--
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/5218893
关键词：
1,25 dihydroxycholecalciferol clinical research glucose clamp technique glucose metabolism glucose tolerance test hormone therapy human subject human therapy evaluation insulin methylprednisolone nephrotic syndrome nutrition related tag pancreatic islet function radioimmunoassay vitamin metabolism

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英文摘要
This study is to examine whether high dose methylprednisolone has an effect on glucose and insulin metabolism as well as 1,25(OH)2 D3 in patients with nephrotic syndrome. Glucose tolerance will be measured by oral glucose tolerance tests. Insulin secretion will be measured by the hyperglycemic clamp method and 1,25(OH)2 D3 will be measured by immunoradiometric assay after preliminary charcoal extraction.
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