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ETHNIC DIFFERENCES IN AN ALCOHOL METABOLIZING ENZYME

ETHNIC DIFFERENCES IN AN ALCOHOL METABOLIZING ENZYME
酒精代谢酶的种族差异
批准号:
5222011
负责人:
Sanjeev Arora
金额:
$0.0万
依托单位:
--
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至

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中文摘要
翻译
酒精中毒和酒精相关性肝病的发病率很高, 在美洲原住民和墨西哥裔美国人中比在高加索人中更高。 P4502E1是一种酶,由于其由慢性炎症诱导而被区分。 乙醇摄入,在这种情况下,它可能占乙醇的80% 间隙 本研究的重点是确定P4502E1是否是 重要的是种族差异的易感性酒精相关的 肝损伤 这将通过筛选淋巴细胞进行研究, 三个人口。
英文摘要
The incidence of alcoholism and alcohol-related liver disease is much higher in Native Americans and Mexican Americans than in Caucasians. P4502E1 is an enzyme distinguished due to its induction by chronic ethanol ingestion, in which case it may account for 80% of ethanol clearance. The focus of this study is to determine whether P4502E1 is important in ethnic differences in susceptibility to alcohol-related liver injury. This will be investigated by screening lymphocytes from three populations.
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Project ECHO Hepatitis C Ambulatory Care Quality Improvement in New Mexico throug
  • 批准号:
    7934632
  • 项目类别:
  • 资助金额:
    $29.87万
  • 财政年份:
    2009
  • 负责人:
    Sanjeev Arora
  • 依托单位:
Project ECHO Hepatitis C Ambulatory Care Quality Improvement in New Mexico throug
  • 批准号:
    8118463
  • 项目类别:
  • 资助金额:
    $30.71万
  • 财政年份:
    2009
  • 负责人:
    Sanjeev Arora
  • 依托单位:
Expansion of Rural Health Care Research Infrastructure through the ECHO Model
  • 批准号:
    7497906
  • 项目类别:
  • 资助金额:
    $50.0万
  • 财政年份:
    2007
  • 负责人:
    Sanjeev Arora
  • 依托单位:
Expansion of Rural Health Care Research Infrastructure through the ECHO Model
  • 批准号:
    7347159
  • 项目类别:
  • 资助金额:
    $50.0万
  • 财政年份:
    2007
  • 负责人:
    Sanjeev Arora
  • 依托单位:
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