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ETHNIC DIFFERENCES IN AN ALCOHOL METABOLIZING ENZYME

ETHNIC DIFFERENCES IN AN ALCOHOL METABOLIZING ENZYME
酒精代谢酶的种族差异
批准号：
5222011
负责人：
Sanjeev Arora
金额：
$0.0万
依托单位：
--
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/5222011
关键词：
Mexican Americans Native Americans alcoholic liver cirrhosis alcoholism /alcohol abuse caucasian American clearance rate clinical research cytochrome P450 disease /disorder proneness /risk enzyme induction /repression human subject lymphocyte racial /ethnic difference

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中文摘要
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英文摘要
The incidence of alcoholism and alcohol-related liver disease is much higher in Native Americans and Mexican Americans than in Caucasians. P4502E1 is an enzyme distinguished due to its induction by chronic ethanol ingestion, in which case it may account for 80% of ethanol clearance. The focus of this study is to determine whether P4502E1 is important in ethnic differences in susceptibility to alcohol-related liver injury. This will be investigated by screening lymphocytes from three populations.
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Project ECHO Hepatitis C Ambulatory Care Quality Improvement in New Mexico throug
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    7934632
  • 项目类别：
  • 资助金额：
    $29.87万
  • 财政年份：
    2009
  • 负责人：
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  • 依托单位：
    UNIVERSITY OF NEW MEXICO
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    8118463
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    2009
  • 负责人：
    Sanjeev Arora
  • 依托单位：
    UNIVERSITY OF NEW MEXICO
Expansion of Rural Health Care Research Infrastructure through the ECHO Model
  • 批准号：
    7497906
  • 项目类别：
  • 资助金额：
    $50.0万
  • 财政年份：
    2007
  • 负责人：
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  • 依托单位：
    UNIVERSITY OF NEW MEXICO
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  • 批准号：
    7347159
  • 项目类别：
  • 资助金额：
    $50.0万
  • 财政年份：
    2007
  • 负责人：
    Sanjeev Arora
  • 依托单位：
    UNIVERSITY OF NEW MEXICO
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