QUANTITATION OF IGE BINDING PROTEIN IN SERA & BLD CELLS OF ALLERGIC PTS

SERA 中 IGE 结合蛋白的定量

• 批准号: 5221415
• 负责人: ATSUSHI YAMAOKA
• 金额: --
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/5221415
• 关键词: asthma; atopic dermatitis; binding proteins; blood cells; clinical research; gene expression; human subject; hypersensitivity; immunoglobulin E; immunopathology diagnosis; inflammation; monocyte; neutrophil; serum

The focus is on IgE-binding protein (e-BP) with an emphasis on establishing a correlation between the expression of this protein and allergic inflammation. The aims are to quantitate e-BP in sera of patients with allergic diseases, including asthma and atopic dermatitis, and to quantitate both total and cell surface e-BP in neutrophils and monocytes of patients with allergic disease.

重点是IgE结合蛋白(e-BP)，重点是 建立该蛋白的表达与 过敏性炎症。其目的是定量检测猪血清中的e-BP。 患有过敏性疾病的患者，包括哮喘和特应性皮炎， 并对中性粒细胞的总E-BP和细胞表面E-BP进行定量 过敏性疾病患者的单核细胞。