VENOGLOBULIN-I(10%) FOR STEROID DEPENDENT ASTHMA AND ATOPIC DERMATITIS

Mazer&Gelfand报告称，在8个月中，情况有了显著改善 激素依赖型哮喘儿童在4岁时接受大剂量静脉注射免疫球蛋白 每周一次，关于所需类固醇的量，皮肤测试 反应性和肺功能测试。另外，Greenberg等人。有 显示皮炎的显著改善和血清的降低 对IVIG治疗严重特应性皮炎的反应。这 临床试验旨在确认和扩展初步研究 使用更集中的静脉注射免疫球蛋白。

Mazer & Gelfand have reported substantial improvement in eight steroid-dependent asthmatic children receiving high dose IVIG at four week intervals, with regard to amount of steroid required, skin test reactivity & pulmonary function tests. Also, Greenberg et al. have demonstrated a substantial improvement in dermatitis & decrease in serum IgE in response to IVIG treatment for severe atopic dermatitis. This clinical trial is designed to confirm and extend the preliminary studies outlined above using a more concentrated form of IVIg.