LIPID PATHWAYS AND LUNG INJURY

脂质通路和肺损伤

• 批准号: 5225585
• 负责人: DAVID BASS
• 金额: --
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/5225585
• 关键词: adult respiratory distress syndrome; arachidonate; asthma; blood lipid; clinical research; eicosanoid metabolism; human subject; lung injury; molecular pathology; pathologic process

Activation of lipid pathways, especially those involving the release and metabolism of arachidonic acid, are key events in diverse pulmonary diseases extending from asthma to the adult respiratory distress syndrome. This program project is an integrated effort to define the molecular and cellular regulation of the complex and interdependent pathways activated in the pathogenesis of lung injury.

脂质途径的激活，特别是那些涉及释放和释放的途径 花生四烯酸的代谢是多种肺部疾病的关键事件 从哮喘到成人呼吸窘迫的疾病 综合症。 该计划项目是一项综合努力，旨在定义 复杂且相互依赖的分子和细胞调节 肺损伤发病机制中激活的途径。