NEUTROPHILS, CYTOKINES AND CYTOKINE RECEPTORS IN SEPTIC SHOCK
NEUTROPHILS, CYTOKINES AND CYTOKINE RECEPTORS IN SEPTIC SHOCK
批准号:
5225555
负责人:
Charles Emory McCall
金额:
$0.0万
依托单位:
--
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
中文摘要
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英文摘要
Human polymorphonuclear leukocytes (PMNL) synthesize, secrete, and
contain specific membrane receptors for, and respond to, the cytokines
II-1 alpha and beta and TNF-beta. Both of these cytokines and PMNL play
an essential role in the pathogenesis of acute disseminated inflammation
with organ failure which may follow microbial infection (septic shock).
Dr. McCall's objective is to show that septic shock in humans is
consistently associated with amplified expression of the IL-1 beta gene.
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会议论文
Redox control over metabolism and mitochondrial bioenergetics directs the course of acute inflammation and sepsis.
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批准号:9916767
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项目类别:
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资助金额:$38.75万
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财政年份:2018
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负责人:Charles Emory McCall
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依托单位:
Redox control over metabolism and mitochondrial bioenergetics directs the course of acute inflammation and sepsis.
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批准号:10398109
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项目类别:
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资助金额:$38.75万
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财政年份:2018
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负责人:Charles Emory McCall
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依托单位:
Redox control over metabolism and mitochondrial bioenergetics directs the course of acute inflammation and sepsis
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批准号:10001885
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项目类别:
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资助金额:$14.42万
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财政年份:2018
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负责人:Charles Emory McCall
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依托单位:
Mitochondrial Biogenesis is Regulated by RelB During Inflammation
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批准号:8696501
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项目类别:
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资助金额:$29.26万
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财政年份:2014
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负责人:Charles Emory McCall
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依托单位:
Mitochondrial Biogenesis is Regulated by RelB During Inflammation
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批准号:9265879
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项目类别:
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资助金额:$29.45万
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财政年份:2014
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负责人:Charles Emory McCall
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依托单位:
Epigenetics of Severe Systemic Inflammation
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批准号:8246552
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项目类别:
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资助金额:$8.94万
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财政年份:2011
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负责人:Charles Emory McCall
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依托单位:
Epigenetics of Severe Systemic Inflammation
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批准号:7847303
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项目类别:
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资助金额:$37.0万
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财政年份:2009
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负责人:Charles Emory McCall
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依托单位:
Epigenetics of Severe Systemic Inflammation
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批准号:8583297
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项目类别:
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资助金额:$36.63万
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财政年份:2009
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负责人:Charles Emory McCall
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依托单位:
Epigenetics of Severe Systemic Inflammation
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批准号:7780157
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项目类别:
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资助金额:$37.0万
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财政年份:2009
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负责人:Charles Emory McCall
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依托单位:
Epigenetics of Severe Systemic Inflammation
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批准号:8389559
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项目类别:
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资助金额:$34.43万
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财政年份:2009
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负责人:Charles Emory McCall
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依托单位:
Epigenetics of Severe Systemic Inflammation
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批准号:7995223
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项目类别:
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资助金额:$36.63万
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财政年份:2009
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负责人:Charles Emory McCall
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依托单位:
Epigenetics of Severe Systemic Inflammation
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批准号:8443459
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项目类别:
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资助金额:$8.08万
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财政年份:2009
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负责人:Charles Emory McCall
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依托单位:
Epigenetics of Severe Systemic Inflammation
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批准号:8196848
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项目类别:
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资助金额:$40.96万
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财政年份:2009
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负责人:Charles Emory McCall
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依托单位:
FUNCTIONAL AND METABOLIC PROPERTIES OF TOXIC NEUTROPHILS AND PATHOGENIC
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批准号:7607666
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项目类别:
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资助金额:$13.78万
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财政年份:2007
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负责人:Charles Emory McCall
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依托单位:
FUNCTIONAL AND METABOLIC PROPERTIES OF TOXIC NEUTROPHILS AND PATHOGENIC
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批准号:7376664
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项目类别:
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资助金额:$14.2万
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财政年份:2006
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负责人:Charles Emory McCall
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依托单位:
NF-kB and Chromatin Changes in Human Sepsis
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批准号:8233964
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项目类别:
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资助金额:$44.2万
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财政年份:2006
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负责人:Charles Emory McCall
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依托单位:
NF-kappaB and Chromatin Changes in Human Sepsis
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批准号:7172995
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项目类别:
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资助金额:$31.35万
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财政年份:2006
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负责人:Charles Emory McCall
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依托单位:
NF-kB and Chromatin Changes in Human Sepsis
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批准号:7099373
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项目类别:
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资助金额:$32.29万
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财政年份:2006
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负责人:Charles Emory McCall
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依托单位:
NF-kB and Chromatin Changes in Human Sepsis
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批准号:8429514
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项目类别:
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资助金额:$58.01万
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财政年份:2006
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负责人:Charles Emory McCall
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依托单位:
NF-kB and Chromatin Changes in Human Sepsis
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批准号:8106714
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项目类别:
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资助金额:$44.21万
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财政年份:2006
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负责人:Charles Emory McCall
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依托单位:
海外基金