INTERNAL VERSUS EXTERNAL SENSING FOR ROTARY BLOOD PUMPS

描述(改编自申请者摘要)：第一阶段的主要目标是 比较内部传感器和外部传感器在以下方面的有效性 旋转血泵的状态监测。这其中的基本假设是 建议将振动传感器直接安装在血泵上 检测早期故障，具有良好的重复性、高灵敏度和 专一性。这一假设将通过使用植入的 加速度计和外置麦克风，用于记录来自 植入动物体内的振动发生器。这种方法将提供信息 类似于种子故障实验。信号频率的各种混频和 表示不同失效模式的强度将使用 振动发生器，来自加速度计和麦克风的信号将 分析以量化传感器的灵敏度和特异度以及 活体组织对信号传递和衰减的影响。此信息将 不仅有助于为第二阶段的工作做出明智的决策 开发状态监测系统，但也将对 开发类似心脏假体的监测系统。 建议的商业应用：不可用

DESCRIPTION (Adapted from applicant's abstract): The main goal of Phase I is to compare the effectiveness of internal sensors versus external sensors for condition monitoring of rotary blood pumps. The fundamental hypothesis of this proposal is that a vibration sensor mounted directly on the blood pump would detect incipient failures with good repeatability, high sensitivity, and specificity. This hypothesis is to be evaluated by using an implanted accelerometer and external microphone to record signals from an animal-implanted vibration generator. This approach will provide information similar to seeded-fault experiments. Various mixes of signal frequencies and strengths representing different failure modes will be introduced using the vibration generator, and signals from the accelerometer and microphone will be analyzed to quantify sensitivity and specificity of sensors as well as the effect of live tissue on signal transmission and damping. This information will not only help in making informed decisions for a Phase II effort for development of a condition monitoring system, but will also be important for development of monitoring systems for similar cardiac prostheses. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE