Internal versus External Sensing for Rotatry Blood Pumps

旋转式血泵的内部与外部传感

• 批准号: 6641370
• 负责人: THOMAS J WALTER
• 金额: $ 54.91万
• 依托单位: FOSTER-MILLER TECHNOLOGIES, INC.
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-06-01 至 2005-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6641370
• 关键词: auxiliary heart prosthesis; biomedical device power system; biomedical equipment development; circulatory assist; cow; implant; medical implant science; monitoring device; phantom model; telemetry; vibration

DESCRIPTION (provided by applicant): The goal of this Phase II program is to develop and demonstrate a compact, highly accurate, and easy-to-use diagnostic system for monitoring the "health" of implanted rotary blood pumps. Based on promising results from Phase I, this blood pump diagnostic system (BPDS) will use only external sensors and, therefore, will be completely nonintrusive and readily extensible to many styles and types of pumps. The Phase II specific aims are to: design and fabricate an integrated BPDS for bedside and in-office physician use; perform in-vitro tests, including "seeded" fault and run-to-failure evaluations demonstrating that the hardware and software effectively extracts the waveforms typical of component failures from the overall vibration signal; and use the BPDS to observe the in-vivo performance of implanted rotary blood pumps. The integrated diagnostics developed in Phase II will be the basis for a Phase III effort applying the system in clinical trials, final refinement and commercialization. The final system will offer significant advantages to future recipients of implanted blood pumps. In addition to ensuring a patient's peace of mind, it will provide physicians with an automatic diagnosis of a pump's health, thereby preventing catastrophic failures that could cost the patient's life.

描述（由申请人提供）： 该第二阶段计划的目标是开发和展示一种紧凑、高度准确且易于使用的诊断系统，用于监测植入式旋转血泵的“健康状况”。基于第一阶段的有希望的结果，该血泵诊断系统（BPDS）将仅使用外部传感器，因此，将是完全非侵入性的，并且易于扩展到许多样式和类型的泵。第II阶段的具体目标是：设计和制造一个集成的BPDS，供床旁和办公室医生使用;进行体外测试，包括“种子”故障和运行至故障评估，证明硬件和软件有效地从整体振动信号中提取组件故障的典型波形;并使用BPDS观察植入式旋转血泵的体内性能。在第二阶段开发的综合诊断将是第三阶段工作的基础，将该系统应用于临床试验、最终改进和商业化。最终的系统将为未来植入血泵的接受者提供显着的优势。除了确保患者的安心，它还将为医生提供泵健康的自动诊断，从而防止可能导致患者生命损失的灾难性故障。