PHARMACOLOGICAL MANAGEMENT OF TEMPOROMANDIBULAR PAIN

描述：(申请人摘要) 颞下颌关节紊乱病是一组具有以下特征的疾病 颞下颌关节和/或咀嚼肌肉的疼痛。 有这些症状的人通常会出现关节卡嗒或爆裂 因此，可能具有有限的开口和降低的功能性 容量。关于疼痛替代疗法有效性的数据 缺乏与TMD相关的(TMP)，患有TMD的人已经 接受广泛的治疗-外科的，非侵入性的，行为的， 和药理作用。 本项目的目的是描述和分析 治疗颞下颌关节痛的药物制剂 在凯撒永久医疗西北地区(KPNW)的成员中 和牙科护理(KPDCP)计划，使用电子信息 以及医疗和牙科治疗记录。对发病率的估计 和接受治疗的TMP的流行率以及TMP的初始疗程 对于1967年至1991年期间的KPNW成员，将从纵向 跨越25年的数据库。吸毒者的药物使用模式 将描述TMP--包括分配的类型、数量和持续时间 并使用通过电子设备获得的信息进行分析 药品数据库。药剂在中国的成本 TMP及其相关后果的管理--减少频率和 疼痛强度和伤残天数-将通过成本模型进行估计 并通过患者问卷调查。

DESCRIPTION: (Applicant's Abstract) Temporomandibular joint disorders are a group of conditions characterized by pain in the temporomandibular joint and/or muscles of mastication. Individuals with these symptoms often present with joint clicking or popping and, consequently, may have limited opening and decreased functional capacity. Data on the effectiveness of alternative treatments for pain associated with TMD (TMP) is lacking, and persons with TMD have been subjected to a wide range of treatments-surgical, noninvasive, behavioral, and pharmacological. The purpose of this project is to describe and analyze the use of pharmaceutical agents in the management of temporomandibular pain (TMP) among members of the Kaiser Permanente Northwest Region medical care (KPNW) and dental care (KPDCP) programs using information available electronically and through medical and dental treatment records. Estimates of incidence and prevalence of treated TMP and of the initial course of therapy for TMP for KPNW members between 1967 and 1991 will be obtained from a longitudinal database spanning 25 years. Patterns of drug use for persons with TMP-including types, numbers, and duration of dispensings-will be described and analyzed using information available through an electronic pharmaceutical database. The costs of pharn1aceutical agents in the management of TMP and associated consequences-decreased frequency and intensity of pain and disability days-will be estimated through a cost model and through patient questionnaires.