RECEIVE-ONLY PHASED ARRAY COIL FOR 3T AND 4T MRI

用于 3T 和 4T MRI 的仅接收相控阵线圈

• 批准号: 6212034
• 负责人: PATRICK J LEDDEN
• 金额: $ 10万
• 依托单位: NOVA MEDICAL, INC.
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-30 至 2001-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6212034
• 关键词: bioimaging /biomedical imaging; biomedical equipment development; magnetic resonance imaging

The investigators plan to prove the feasibility of receive-only phased array coil technology for human brain MR imaging studies at high field strengths (3T-4T). Such a coil will be unique in high field human applications. Improvements in brain imaging at 3T and 4T have been achieved without the benefit of the preferred method for high sensitivity imaging at lower fields: the use of volume coils for homogeneous excitation together with phased arrays of surface coils for high SNR reception. The desirability of this system stems from the combination of the homogeneous excitation provided by the volume coil and the unsurpassed sensitivity of phased array coil detectors. Our previous work developing these coils for neuroimaging at 1.5T has shown a 50-300 percent improvement in sensitivity compared to volume coil receivers for large region of the brain. The benefits are expected to be even greater at 3T and 4T since radiation losses at high frequency (with a frequency dependence approaching v^4) gives further motivation for the use of small surface coil arrays. The receive-only phased array coils proposed in this application will be developed for use with the high frequency homogeneous transmit coils which have already been developed by Nova Medical. Phase I of the current proposal will develop prototype phased array coils for neuroimaging, validate the active decoupling between transmit and receive subsystems and demonstrate the potential advantages of the system in sensitivity and regional coverage. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE

研究人员计划证明仅接收相控阵的可行性 用于高场强下人脑 MR 成像研究的线圈技术 （3T-4T）。这种线圈在高场人体应用中将是独一无二的。 3T 和 4T 脑成像的改进已经在没有 在较低视场进行高灵敏度成像的首选方法的优点： 使用体积线圈与相控阵进行均匀激励 用于高信噪比接收的表面线圈。该系统的可取性源于 来自体积线圈提供的均匀激励的组合 以及相控阵线圈探测器无与伦比的灵敏度。我们之前的 开发这些用于 1.5T 神经成像线圈的工作已显示出 50-300% 与大面积的体积线圈接收器相比，灵敏度有所提高 大脑的。预计 3T 和 4T 的好处会更大，因为 高频辐射损耗（频率依赖性接近 v^4）进一步推动了小表面线圈阵列的使用。 本申请中提出的仅接收相控阵线圈将是 开发用于与高频均匀发射线圈一起使用，该线圈具有 已经由 Nova Medical 开发。当前提案的第一阶段将 开发用于神经成像的原型相控阵线圈，验证有源 发送和接收子系统之间的解耦并演示 该系统在灵敏度和区域覆盖方面的潜在优势。 拟议的商业应用：不可用