AN INTRA-ORAL SALIVA VACUUMING APPLIANCE FOR SIALORRHEA

一种口腔内流涎吸痰器

• 批准号: 6209578
• 负责人: CARRIE C BROWN
• 金额: $ 10万
• 依托单位: INNOVATIVE HUMAN SERVICES, INC.
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-20 至 2002-03-19
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6209578
• 关键词: assistive device /technology; clinical research; human subject; orthodontic appliances; rehabilitation; salivary disorder; salivation; technology /technique development

Sialorrhea (i.e., drooling) is a profound social and hygienic problem for individuals with this condition. Innovative Human Services, Inc. developed the Chin Dry System(tm) (CDS) technology that vacuums unwanted saliva and stores it for disposal. The CDS was used to pilot test an intra-oral appliance that successfully vacuumed unswallowed saliva from inside the mouth before it spilled from the mouth and subjects remained dry. The primary aim of this project is for collaborators Innovative Human Services, Inc., Texas Scottish Rite Hospital for Children, and Baylor College of Dentistry to explore the feasibility of researching, developing and testing the building of two customized intra-oral appliance prototypes that vacuum unwanted saliva from inside the used mouth prior to a saliva spill. 8-10 research subjects with saliva overflow problems will be assigned to two groups and test each of the prototypes for 4 months. The intra-oral appliances will incorporate standard and approved dental parts and fabrication techniques. Researchers will investigate advantages and disadvantages of removing saliva from the mouth plus the psychological implications of the appliance on the research subjects and caregivers. Any skilled orthodontic professional can adopt this technology. PROPOSED COMMERCIAL APPLICATION: The customized intra-oral appliances will be packaged as an option of the CDS. Production techniques will follow standard orthodontic practices for building oral appliances. Researchers expect the cost to be around $500 for the appliance and $300 for the CDS Technology. If this technology were successful, researchers would explore reversing the vacuuming capabilities of the CDS so that artificial saliva is sprayed into the mouth for xerostomia patients. It could be as an intra-oral medicine delivery system. There are approximately 436,000 potential consumers who drool not counting potential users with xerostomia or benefitting from intra-oral medicine delivery.

流涎（即，流口水）对于患有这种病症的个体来说是一个深刻的社会和卫生问题。创新人类服务公司开发了Chin Dry System（TM）（CDS）技术，该技术可将不需要的唾液抽真空并储存起来以备处置。CDS被用于初步测试一种口腔内装置，该装置成功地将未吞咽的唾液从口腔内抽真空，然后唾液从口腔溢出，受试者保持干燥。该项目的主要目的是为合作者创新人类服务公司，德克萨斯苏格兰儿童医院和贝勒牙科学院，探索研究，开发和测试两种定制的口腔内器具原型的可行性，这些原型在唾液溢出之前从使用过的口腔内真空不需要的唾液。8-10有唾液溢出问题的研究受试者将被分配到两个组，并对每个原型进行为期4个月的测试。口腔内矫正器将采用标准和批准的牙科部件和制造技术。研究人员将调查从口腔中去除唾液的优点和缺点，以及该设备对研究对象和护理人员的心理影响。任何熟练的正畸专业人员都可以采用这项技术。拟议的商业应用：定制的口内矫治器将作为CDS的一个选项进行包装。生产技术将遵循制造口腔用具的标准正畸实践。研究人员预计，该设备的成本约为500美元，CDS技术的成本约为300美元。如果这项技术成功，研究人员将探索逆转CDS的真空功能，以便将人工唾液喷入口腔干燥症患者的口中。它可以作为口腔内药物输送系统。大约有436，000名潜在消费者流口水，不包括患有口干症或受益于口腔内药物输送的潜在用户。