NOVEL APPROACH TO DELIVERING EXCIMER UV ENERGY FOR PRK

描述：（改编自研究者摘要）：屈光 角膜切开术，屈光矫正手术的主要方法 错误，有一个主要的弱点-无法准确预测 手术结果对个体患者。 准分子紫外（UV） 激光器提供了一个潜在的解决这个问题的办法，如果他们耦合 一个有效的激光发射系统 屈光性角膜切除术（PRK），或基于激光的角膜手术，可以 可以通过许多类型的激光传输配置来实现。 的 两种最成功的方法是扩大虹膜技术， 这是一种简单的实施方式，但仅限于治疗近视， 扫描点技术，提供最大的治疗灵活性 但是治疗时间延长并且输送硬件复杂。 FEO Medical建议向角膜提供复杂的矫正模式 在使用基于新技术的显著减少的治疗时间中， 在一个数字的，微机械设备，包括一个640 x480阵列， 单独控制的微镜，耦合到数字角膜， 地形系统 在第一阶段，计算机生成的测试图案将被蚀刻到 各种紫外线敏感测试材料。 所得到的蚀刻图案将 与已知模式进行比较，以衡量项目的成功 并为第二阶段的工作奠定基础， 和人类研究。

DESCRIPTION: (Adapted From The Investigator's Abstract): Refractive keratotomy, the dominant method for surgical correction of refractive error, has one main weakness - the inability to predict accurately the outcome of surgery for an individual patient. Excimer ultraviolet (UV) lasers offer a potential solution to this problem if they are coupled to an effective laser delivery system. Photorefractive Keratectomy (PRK), or laser-based corneal surgery, can be implemented through many types of laser delivery configurations. The two most successful ones are the expanding iris technique, which offers a simple implementation but is limited to treating myopia, and the scanning spot technique which offers the greatest treatment flexibility but with extended treatment times and complicated delivery hardware. FEO Medical proposes to deliver complex correction patterns to the cornea in substantially reduced treatment times using a novel technique based on a digital, micromachined device, consisting of a 640x480 array of individually- controlled micromirrors, coupled to a digital corneal topography system. During Phase I, computer-generated test patterns will be etched onto various UV-sensitive test materials. The resulting etch patterns will be compared to the known patterns to measure the success of the project and establish a basis for the Phase II effort which will involve animal and human studies.