DETECTING CORNEAL STRIAE AFTER LASIK SURGERY

LASIK 手术后检测角膜条纹

• 批准号: 6292982
• 负责人: ROY E WILLIAMS
• 金额: $ 9.99万
• 依托单位: FEO MEDICAL, INC.
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-03-09 至 2001-09-08
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6292982
• 关键词: bioimaging /biomedical imaging; biomedical equipment development; cornea; cornea disorder; eye laser surgery; imaging /visualization /scanning; infrared radiation; keratoplasty

DESCRIPTION: Excimer laser refractive surgery is a very poplar method for providing patients with better vision. Experts predict 1.7 million American patients will have this procedure performed this year. Approximately 95 percent of these patients will have he procedure termed LASIK. There are some important advantages that have caused LASIK to become he dominant technique. However, it has one drawback, that of striae or corneal wrinkling, due to the thin "flap" hat is created. Striae can cause vision problems ranging from glare to decreased acuity ad is created when the flap is not reattached uniformly. Most surgeons agree the problems exists in approximately 2-3 percent of LASIK patients, which means 40,000 patients will experience this problem this year. FEO Medical proposes to scan off-axis, monochromatic, near-infrared illumination around the cornea to create an edge enhancement effect to expose striae. An IR camera will capture each "scan" image followed by processing for edge variations (possible striae). During Phase I, FEO Medical will construct an IR ring illuminator; illuminate and videotape LASIK patients with possible striae: and design and implement an algorithm to detect the striae thus proving feasibility. This feasibility will establish a basis for the Phase II study and subsequent commercialization. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE

描述：准分子激光屈光手术是一种非常受白杨的方法， 为患者提供更好的视力。专家预测170万美国人 病人将在今年进行这项手术。大约95% 这些患者将有他的程序称为LASIK。有一些重要 这些优点使LASIK成为主导技术。但 有一个缺点，即由于薄的“瓣”， 帽子是创造出来的。条纹会导致视力问题， 当瓣没有均匀地重新附着时，产生了降低的敏锐度AD。最 外科医生认为大约2- 3%的LASIK手术存在问题， 患者，这意味着今年将有40，000名患者遇到这个问题。 FEO Medical建议扫描离轴、单色、近红外 角膜周围的照明，以产生边缘增强效果， 条纹红外相机将捕获每个“扫描”图像，然后进行处理， 边缘变化（可能有条纹）。在第一阶段，FEO Medical将建造 红外环形照明器;照明和录像LASIK患者可能 条纹：并设计和实现一个算法来检测条纹，从而证明 可行性这一可行性将为第二阶段研究奠定基础， 随后的商业化。 拟议商业应用：不可用