MODULATION RESPONSE IN THE INFERIOR COLLICULUS

下丘的调节反应

• 批准号: 6175737
• 负责人: MARK N KVALE
• 金额: $ 4.63万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-01 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6175737
• 关键词: cats; cell type; inferior colliculus; neurons; neurophysiology; single cell analysis; sound perception; stimulus /response

DESCRIPTION The overall goal of this project is to measure and quantitatively characterize the response of neurons in the inferior colliculus (IC) to acoustic stimuli. The specific aims of this project are to characterize the non-linear, spectro- temporal and adaptive behaviors of single units in the central nucleus of the inferior colliculus using custom designed stimuli for this purpose. The inferior colliculus is a central way-station in the auditory system which plays a major role in the processing of complex sounds, such as speech. Characterizing these behaviors will allow one to better understand and predict how the mammalian IC processes complex sounds and ultimately to contribute a better understanding of the pathologies in speech recognition and language acquisition.

描述 该项目的总体目标是测量并定量表征下丘 (IC) 神经元对声刺激的反应。该项目的具体目标是使用为此目的定制设计的刺激来表征下丘中央核中单个单元的非线性、谱时和适应性行为。下丘是听觉系统的中央中转站，在处理复杂声音（例如语音）中发挥着重要作用。表征这些行为将使人们能够更好地理解和预测哺乳动物 IC 如何处理复杂的声音，并最终有助于更好地理解语音识别和语言习得的病理学。