EXTERNAL VALIDITY OF THE DSM IV SUBTYPES OF ADHD

描述(改编自申请者摘要)： 建议的研究是检查DSM-IV亚型的外部效度 注意缺陷多动障碍，主要包括 注意力不集中(IA)、多动/冲动(HI)和混合型(COM)亚型。 精神疾病共病与执行功能表现的关系 (EF)任务将在不同组之间进行比较。有一些证据表明 不同群体之间的精神障碍，但需要做更多的工作 在这一地区完成。据预测，亚型将有 不同的精神病学相关，与IA亚型相关更多 高度内在化障碍与HI和COM组相关 外部性障碍的发生率更高。此外，几乎没有什么工作 已经对DSM-IV亚型的神经心理学特征进行了研究。它是 预测神经心理测试将会是敲击抑制 组内有不同程度的损害，仅有HI和COM亚型 显示出与抑制能力直接相关的变量的损害， 如委员会对戈登和抑制百分比的错误和 停止任务上的停止信号反应时间(SSRT)。差异的证据 精神病学档案和神经心理学档案将支持 DSM-IV亚型的外部效度。

DESCRIPTION (Adapted from Applicant's Abstract): The overall goal of the proposed research is to examine the external validity of the DSM-IV subtypes of Attention Deficit Hyperactivity Disorder, which include primarily inattentive (IA), hyperactive/impulsive (HI) and combined (COM) subtypes. Profiles of psychiatric comorbidity and performance on executive function (EF) tasks will be compared among the groups. There is some evidence of differential psychiatric disorders among the groups, but more work needs to be done in this area. It is predicted that the subtypes will have differential psychiatric correlates, with the IA subtype correlating more highly with internalizing disorders and the HI and COM groups correlating more highly with externalizing disorders. Further, very little work has been done on the neuropsychological profiles of the DSM-IV subtypes. It is predicted that the neuropsychological tests that tap inhibition will be differentially impaired in the groups, with only the HI and COM subtypes showing impairment on the variables directly relating to ability to inhibit, such as the commission errors on the Gordon and percent of inhibition and Stop Signal Reaction Time (SSRT) on the Stop Task. Evidence of differential psychiatric profiles and neuropsychological profiles would lend support for the external validity of the DSM-IV subtypes.